Honeywell North 7582P100L Acid Gas P100 Respirator Cartridge
EDITORIAL REVIEW: 4.5/5 WC Safety Review — Honeywell North 7582P100L Acid Gas P100 Cartridge Best For: Acid gas hazards — chlorine, hydrogen chloride, sulfur dioxide, and formaldehyde — combined wi...
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Best For: Acid gas hazards — chlorine, hydrogen chloride, sulfur dioxide, and formaldehyde — combined with P100 particulate protection on North 5500, 7700, 5400, or 7600 series respirators. Chemical processing, laboratory fume exposure, hazmat response, and industrial hygiene applications where both gas and particulate hazards co-exist.
Not For: Organic vapor without acid gas co-hazard (use the 7581P100L OV/P100 instead), ammonia or methylamine atmospheres, carbon monoxide, or any environment requiring an SCBA or supplied-air respirator. Not compatible with 3M, Moldex, or any non-North bayonet facepiece.
Bottom Line: A purpose-built combination cartridge for acid gas plus P100 duty — the 7582P100L delivers high-efficiency particulate protection alongside acid gas coverage in a single North bayonet unit; when organic vapor is also in the atmosphere, the 7583P100L (OV/AG/P100) is the correct step-up.
Editorial assessment by the WC Safety Editorial Team. WC Safety did not laboratory-test this product; scoring reflects published manufacturer specifications, application fit, compatibility, safety limitations, and category expertise.
Honeywell North 7582P100L Overview
The Honeywell North 7582P100L is a NIOSH-approved acid gas + P100 combination cartridge that protects against acid gases — including chlorine, hydrogen chloride (HCl), sulfur dioxide (SO₂), and formaldehyde — while simultaneously filtering ≥99.97% of oil and non-oil airborne particles. It mounts on the universal North bayonet connection used by North 5500 half-face, 7700 half-face, 5400 full-face, and 7600 full-face respirators, and is sold as a pair. Order the 7582P100L when your hazard assessment identifies acid gases and particulate as co-present respiratory risks and your facepiece is a Honeywell North respirator.
This is a combination cartridge — both gas-phase and particulate protection in one unit — which makes it the workhorse choice for chemical plant maintenance, laboratory environments with fume and dust exposure, hazmat response, and industrial cleaning operations involving acid gases. For the full breakdown of how combination cartridges fit the respirator selection hierarchy, see the Honeywell North cartridge guide and the how to choose a respirator cartridge guide. Browse all in-family options in the Honeywell North respirator filters and cartridges collection.
Where the 7582P100L Fits in Respirator Selection
Combination cartridge selection comes down to two questions: what gases and vapors are present, and what particulate hazard is alongside them. For the 7582P100L, the confirmed hazard profile is acid gas + airborne particulate with no organic vapor component. If your profile differs even slightly, a different cartridge in the North 75xx family is the right call.
- Acid gas + P100 particulate only → the 7582P100L is the correct cartridge.
- Organic vapor + P100 particulate, no acid gas → the 7581P100L (OV/P100).
- Organic vapor + acid gas + P100 particulate → the 7583P100L (OV/AG/P100).
- Ammonia or methylamine + P100 → the 7584P100L (NH₃/MA/P100).
- Mercury vapor or chlorine + P100 → the 75852P100L (Hg/Cl/P100).
- Multi-contaminant + P100 → the 75SCP100L (multi-contaminant/P100).
- Particulate only, no gas → the 75FFP100 P100 filter.
- Not sure which class you need? The respirator filter types explained guide and the respirator cartridge color chart clarify the decision by hazard class and label color.
Who Should Buy the Honeywell North 7582P100L?
Buy the 7582P100L if your workplace hazard assessment identifies acid gases — chlorine, hydrogen chloride, sulfur dioxide, or formaldehyde — alongside airborne particulate, and your facepiece is a North 5500, 7700, 5400, or 7600 series respirator. This cartridge is common in chemical manufacturing, water treatment facilities, industrial cleaning, laboratory settings, and any environment where acid gas and dust or aerosol hazards co-exist.
Choose a different cartridge if:
- Organic vapors are also present in your atmosphere → the 7583P100L (OV/AG/P100) adds organic vapor coverage.
- Your hazard is organic vapor without acid gas → the 7581P100L (OV/P100).
- Ammonia or methylamine is the gas hazard → the 7584P100L.
- You need acid gas coverage without particulate → the N75002L acid gas cartridge (gas only, no P100).
- You run a 3M, Moldex, or any non-North bayonet respirator → North bayonet cartridges are mechanically incompatible with other brands.
What Does the 7582P100L Protect Against?
| Hazard | 7582P100L Fit | Buyer Guidance |
|---|---|---|
| Chlorine (Cl₂) | ✅ Acid Gas | Covered under acid gas approval |
| Hydrogen chloride (HCl) | ✅ Acid Gas | Common in chemical processing and lab work |
| Sulfur dioxide (SO₂) | ✅ Acid Gas | Covered under acid gas approval |
| Formaldehyde (HCHO) | ✅ Acid Gas | Included in acid gas coverage |
| Particulate (dust, mist, fumes) | ✅ P100 (≥99.97%) | Oil and non-oil aerosols; highest NIOSH particulate class |
| Organic vapors (solvents) | ❌ No | Use 7583P100L (OV/AG/P100) |
| Ammonia / methylamine | ❌ No | Use 7584P100L |
| Carbon monoxide (CO) | ❌ No | CO requires supplied air or SCBA |
| Mercury vapor | ❌ No | Use 75852P100L |
What the 7582P100L Does NOT Protect Against
- Organic vapors (solvents)
- Ammonia / methylamine
- Carbon monoxide
- Mercury vapor
- Hydrogen sulfide (H₂S) at high concentrations
- Oxygen deficiency
- Unknown atmospheres
- IDLH conditions
- Hydrogen fluoride (HF)
- Asphyxiants
Safety: The 7582P100L is an acid gas + P100 combination cartridge only — it provides no organic vapor, ammonia, carbon monoxide, or mercury vapor protection, and no cartridge adds oxygen to the breathing air. It fits only the North bayonet connection and cannot be installed on 3M, Moldex, GVS, or any other brand of facepiece. Oxygen-deficient atmospheres, unknown gas environments, and IDLH conditions require supplied-air respirators, SCBA, or another control specified by a qualified safety professional. Cartridge selection must follow a written respiratory protection program and hazard assessment per OSHA 29 CFR 1910.134.
Best Applications for the 7582P100L
Chemical Processing & Plant Maintenance
The 7582P100L is designed for environments where acid gases — chlorine, HCl, SO₂ — are present alongside airborne dust or aerosol. Chemical plant maintenance, reactor cleaning, and process equipment work routinely generate both gas-phase and particulate hazards, making this combination cartridge a direct specification match. Pair it with a 7580P100 P100 filter reference for particulate-only backup when acid gas exposure is not present in an adjacent task. See the full Honeywell North respirator filters and cartridges collection for the complete North 75xx lineup.
Water Treatment & Chlorination
Chlorine gas exposure is a primary hazard in water treatment and disinfection operations. The 7582P100L's acid gas layer addresses chlorine and HCl directly, and the P100 particulate layer covers any aerosol or dust generated by handling chlorination chemicals or adjacent maintenance tasks. Consult the respirator filter types explained guide to confirm the cartridge class against your site-specific SDS hazard data before placing a bulk order.
Laboratory & Industrial Hygiene Work
Laboratory environments that handle acid reagents — hydrochloric acid, sulfuric acid, formaldehyde fixatives — produce both gas-phase and aerosol exposure when samples are processed or spills occur. The 7582P100L's combination protection makes it a practical single-cartridge answer for lab respiratory programs on North facepieces. Review the cartridge selection guide to confirm the 7582P100L covers your specific acid reagents before finalizing your hazard assessment.
Industrial Cleaning & Surface Treatment
Acid-based cleaning compounds — used in metal surface treatment, descaling, and industrial sanitization — generate acid gas vapors and often fine mist or aerosol. The 7582P100L covers both hazard types in a single cartridge, reducing the need for separate particulate filter attachments and simplifying cartridge change-out tracking. For environments that also involve solvent cleaning in the same shift, consult the best Honeywell North cartridge guide to evaluate whether the 7583P100L (OV/AG/P100) is the better all-shift solution.
Honeywell North 7582P100L Pros & Cons
| Pros | Cons |
|---|---|
| NIOSH-approved acid gas + P100 combination — dual protection in one cartridge unit | No organic vapor protection — step up to 7583P100L when solvents are also present |
| P100 class (≥99.97%) — highest NIOSH particulate efficiency, effective against oil and non-oil aerosols | North bayonet only — not compatible with any other brand facepiece |
| Universal North bayonet fits all four North facepiece series (5500, 7700, 5400, 7600) | No ammonia, CO, or mercury vapor protection |
| Covers formaldehyde alongside chlorine, HCl, and SO₂ in a single unit | Cartridge change-out interval requires written ESLI program — no visual end-of-service-life indicator |
| Sold as a pair — covers both ports of half-face and full-face respirators | Higher price point than gas-only or particulate-only cartridges |
Compatible Honeywell North Respirators
The 7582P100L uses the universal North bayonet connection shared by all North 75xx combination cartridges and filters. This connection is exclusive to the Honeywell North respirator platform — it does not fit 3M bayonet facepieces, Moldex bayonet facepieces, GVS respirators, or any other brand.
| Respirator | Type | Compatible? | Notes |
|---|---|---|---|
| North 5500 Series | Half-face | ✅ Yes | Universal North bayonet connection |
| North 7700 Series | Half-face | ✅ Yes | Universal North bayonet connection |
| North 5400 Series | Full-face | ✅ Yes | Universal North bayonet connection |
| North 7600 Series | Full-face | ✅ Yes | Universal North bayonet connection |
| 3M 6000 / 6500 / 7500 / 7800S series | Half/Full-face | ❌ No | 3M bayonet — physically incompatible |
| Moldex 7000 / 9000 series | Half/Full-face | ❌ No | Moldex bayonet — physically incompatible |
| Any other brand respirator | Any | ❌ No | North bayonet is brand-exclusive |
The North bayonet is a universal connection across the entire Honeywell North 75xx cartridge and filter family, meaning any North 75xx cartridge or filter mounts the same way on any compatible North facepiece. Browse sibling cartridges in the Honeywell North respirator filters and cartridges collection.
7582P100L vs Other Honeywell North 75xx Combination Cartridges
| Cartridge | Gas Protection | Particulate | Choose If |
|---|---|---|---|
| 7582P100L | Acid gas (Cl₂, HCl, SO₂, HCHO) | P100 | Acid gas + particulate; no OV present |
| 7580P100 | None (particulate only) | P100 | Particulate only; no gas hazard |
| 7581P100L | Organic vapor | P100 | OV + particulate; no acid gas |
| 7583P100L | OV + acid gas | P100 | OV + acid gas + particulate |
| 7584P100L | Ammonia / methylamine | P100 | Ammonia / methylamine + particulate |
| 75852P100L | Mercury vapor + chlorine | P100 | Mercury vapor or chlorine + particulate |
| 75SCP100L | Multi-contaminant (OV/AG/AM) | P100 | Multiple gas classes + particulate |
7582P100L vs 7583P100L — Acid Gas vs Acid Gas + Organic Vapor
The 7582P100L and the 7583P100L are the most commonly compared cartridges in this family because they share identical acid gas and P100 particulate protection — the only difference is that the 7583P100L adds an organic vapor layer. If your hazard assessment confirms that solvents, coatings, or hydrocarbon vapors are absent from the work environment, the 7582P100L is the correct lower-cost selection. If there is any organic vapor co-present — even as a nuisance-level background exposure — the 7583P100L is the safer specification choice. When in doubt, consult your industrial hygienist and the cartridge selection guide.
7582P100L vs N75002L — Combination vs Gas-Only
The N75002L is the gas-only acid gas cartridge in the North family — it covers the same acid gas hazards (chlorine, HCl, SO₂, formaldehyde) but contains no P100 particulate filter media. Choose the N75002L only when your hazard assessment confirms that no significant particulate, dust, mist, or aerosol is co-present. The moment airborne particles are part of the hazard profile, the 7582P100L's P100 layer is required. For a detailed breakdown of how to evaluate gas-only versus combination cartridge needs, see the respirator filter types explained guide.
7582P100L vs 75SCP100L — Targeted vs Multi-Contaminant
The 75SCP100L is a multi-contaminant P100 cartridge that covers a broader spectrum of gas classes — organic vapor, acid gas, ammonia, and methylamine — in addition to P100 particulate. If your site has multiple concurrent gas hazards or the hazard profile shifts between tasks in the same shift, the 75SCP100L simplifies program management. If your hazard is cleanly defined as acid gas + particulate with no other gas class present, the 7582P100L is the more cost-efficient and appropriately targeted specification. See the best Honeywell North cartridge guide for a full side-by-side evaluation.
Honeywell North 7582P100L Quick Answers
What is the Honeywell North 7582P100L?
The Honeywell North 7582P100L is a NIOSH-approved acid gas and P100 combination respirator cartridge. It protects against acid gases — including chlorine, hydrogen chloride, sulfur dioxide, and formaldehyde — and filters ≥99.97% of airborne oil and non-oil particles. It mounts on the universal North bayonet connection on North 5500, 7700, 5400, and 7600 series respirators and is sold as a pair.
What facepieces does the 7582P100L fit?
The 7582P100L fits all Honeywell North respirators that use the universal North bayonet connection: the North 5500 half-face, North 7700 half-face, North 5400 full-face, and North 7600 full-face series. It does not fit 3M bayonet, Moldex bayonet, or any non-North respirator facepiece.
Does the 7582P100L protect against organic vapors?
No. The 7582P100L is rated for acid gases and P100 particulate only — it contains no organic vapor sorbent. When solvents, coatings, or hydrocarbon vapors are also present in the atmosphere, the 7583P100L (OV/AG/P100) is the correct selection.
What is the P100 rating and what does it mean?
P100 is NIOSH's highest particulate filter class, requiring ≥99.97% filtration efficiency for both oil and non-oil aerosols. The "P" designation indicates the filter is oil-proof — suitable for oil mist and aerosol environments — unlike the N-class (oil not resistant) or R-class (oil resistant). The P100 vs N95 guide covers the class distinctions in detail.
How many cartridges come in a 7582P100L pack?
The 7582P100L is sold as one pair — two cartridges — the standard quantity for a dual-port half-face or full-face respirator. Verify the current pack quantity on the product listing before placing a bulk order.
Does the 7582P100L protect against chlorine gas?
Yes. Chlorine (Cl₂) is within the acid gas protection class that the 7582P100L is approved for. It is commonly specified in water treatment, chemical processing, and industrial cleaning environments where chlorine exposure is a documented hazard.
Is the 7582P100L compatible with 3M respirators?
No. The 7582P100L uses the North bayonet connection, which is physically incompatible with 3M bayonet facepieces. It cannot be installed on any 3M 6000, 6500, 7000, 7500, or 7800S series respirator, nor on any Moldex or other-brand facepiece.
Honeywell North 7582P100L Specifications
| Brand | Honeywell North |
| Model / SKU / MPN | 7582P100L |
| NIOSH Approval | Acid Gas + P100 combination |
| Gas / Vapor Protection | Acid gases: chlorine (Cl₂), hydrogen chloride (HCl), sulfur dioxide (SO₂), formaldehyde (HCHO) |
| Particulate Protection | P100 — ≥99.97% filtration efficiency (oil and non-oil aerosols) |
| Connection Type | Universal North bayonet |
| Compatible Facepieces | North 5500 (half-face), North 7700 (half-face), North 5400 (full-face), North 7600 (full-face) |
| Incompatible With | 3M bayonet, Moldex bayonet, GVS, or any non-North bayonet facepiece |
| Package Quantity | 1 pair (2 cartridges) |
| Current Price | $50.60 (verify current price on listing) |
| Replacement Interval | Per employer's written change-out schedule or ESLI program per OSHA 29 CFR 1910.134 |
Helpful Buying Guides
- Honeywell North Cartridge Guide — Full Selection Reference
- Best Honeywell North Respirator Filters and Cartridges
- How to Choose a Respirator Cartridge
- Respirator Filter Types Explained
- P100 vs N95 — What's the Difference?
- Respirator Cartridge Color Chart
- Organic Vapor vs P100 — Which Do You Need?
Honeywell North 7582P100L Frequently Asked Questions
What does the Honeywell North 7582P100L protect against?
The 7582P100L is a combination cartridge that provides acid gas protection — covering chlorine, hydrogen chloride, sulfur dioxide, and formaldehyde — plus P100 particulate filtration at ≥99.97% efficiency for both oil and non-oil aerosols. It does not protect against organic vapors, ammonia, carbon monoxide, or mercury vapor.
What respirators is the 7582P100L compatible with?
The 7582P100L is compatible with all Honeywell North respirators that use the universal North bayonet connection: North 5500 half-face, North 7700 half-face, North 5400 full-face, and North 7600 full-face series. It is not compatible with any 3M, Moldex, GVS, or other brand facepiece.
Does the 7582P100L fit 3M or Moldex respirators?
No. The North bayonet connection is brand-exclusive to the Honeywell North platform. The 7582P100L cannot physically mount on 3M bayonet facepieces (6000, 6500, 7500, 7800S series), Moldex bayonet facepieces (7000, 9000 series), or any other brand respirator. Attempting to force an incompatible cartridge onto a facepiece creates a seal failure and a serious respiratory hazard.
When should I choose the 7582P100L over the 7583P100L?
Choose the 7582P100L when your hazard assessment confirms acid gas and particulate are the only respiratory hazards and organic vapor is absent from the environment. Choose the 7583P100L when organic vapors — solvents, coatings, hydrocarbons — are also present alongside acid gases, because the 7583P100L adds an organic vapor layer on top of the same acid gas and P100 protection.
What is the difference between the 7582P100L and N75002L?
The N75002L is a gas-only acid gas cartridge — same acid gas coverage (chlorine, HCl, SO₂, formaldehyde) but no P100 particulate filter. The 7582P100L is the combination version: identical acid gas protection plus P100 particulate filtration in one unit. Use the N75002L only when no airborne particulate hazard is present; use the 7582P100L when both acid gas and particulate are co-present hazards.
How many cartridges come in the 7582P100L package?
The 7582P100L is sold as one pair — two cartridges — the standard unit for a dual-port half-face or full-face respirator. Both cartridges must be installed together; never operate a dual-port respirator with only one cartridge seated.
Does the 7582P100L protect against formaldehyde?
Yes. Formaldehyde is within the acid gas protection class covered by the 7582P100L. It is a commonly specified cartridge in laboratory, histology, and embalming environments where formaldehyde exposure is a documented hazard alongside particulate risk.
Can the 7582P100L be used for spray painting?
The 7582P100L covers acid gas and P100 particulate — it does not protect against organic vapors from paint solvents. For spray painting, the correct cartridge depends on your specific paint chemistry: if acid gases are not present but organic vapor and particulate are, use the 7581P100L (OV/P100). If both acid gases and organic vapors co-exist in your painting environment (uncommon but possible in specialty coating work), the 7583P100L (OV/AG/P100) is the specification.
When should the 7582P100L be replaced?
Replace the 7582P100L when you detect odor, taste, or irritation breakthrough; when the cartridge is physically damaged or wet; or according to your employer's written cartridge change-out schedule established under OSHA 29 CFR 1910.134. Combination cartridges with activated carbon for gas adsorption do not have a visual end-of-service-life indicator for the gas layer — a written or software-based change-schedule is required.
Is the 7582P100L P100 layer effective against oil mists?
Yes. The P100 class is oil-proof (the "P" designation in NIOSH naming indicates resistance to oil aerosols), so the 7582P100L's particulate layer is effective against oil-based aerosols, mists, and fumes as well as non-oil particles. This makes it suitable for environments where both acid gas vapors and oil-based aerosols are co-present hazards.
What is the best Honeywell North cartridge for environments with both acid gas and organic vapor?
The 7583P100L is the correct specification when organic vapor and acid gas are both present alongside particulate. It adds organic vapor protection to the same acid gas and P100 particulate coverage as the 7582P100L. For multi-gas environments that also include ammonia or methylamine, the 75SCP100L multi-contaminant P100 cartridge provides the broadest coverage in one North cartridge unit.
Does the 7582P100L work for silica dust protection?
Yes — the P100 particulate layer at ≥99.97% efficiency is effective against respirable crystalline silica dust. If silica is the primary hazard and no acid gas is present, a lower-cost option such as the 7580P100 P100 filter or a prefilter combination may be more appropriate. Consult the best respirator for silica dust guide for application-specific guidance.
Written by Steven Eaton, WC Safety Editorial — industrial PPE and respiratory protection specialist with experience specifying NIOSH-approved cartridges for chemical, manufacturing, and laboratory environments.
Reviewed by: WC Safety Editorial Team for standards accuracy, cartridge selection guidance, and compatibility verification.
Cartridge class selection must follow a written respiratory protection program, workplace hazard assessment, and industrial hygiene evaluation per OSHA 29 CFR 1910.134. For combination cartridges without an electronic end-of-service-life indicator, OSHA requires a documented scheduled change-out interval — consult a Certified Industrial Hygienist (CIH) or Certified Safety Professional (CSP) to establish the correct interval for your specific application.
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