Honeywell North 7582P100L vs 7583P100L: OV/P100 vs OV/AG/P100 (2026)

Honeywell North 7582P100L vs 7583P100L: OV/P100 vs OV/AG/P100 (2026)

Choosing between the Honeywell North 7582P100L and the 7583P100L comes down to a single question: is organic vapor present in your hazard environment alongside the acid gas and particulate? The 7582P100L covers acid gas and P100 particulate but carries no organic vapor protection. The 7583P100L adds a full organic vapor layer — making it the correct cartridge when solvents, paint thinners, or other organic vapors share the air with acid gases and dust. Both mount on the same North bayonet connection and are sold as a pair.

Quick Answer: Which Cartridge Should You Buy?

If your hazard assessment confirms acid gas and particulate only — no organic vapors — the 7582P100L is the purpose-built, lower-cost choice. If your environment also has organic vapors such as solvents, paint, or coating residues alongside the acid gas and particulate, the 7583P100L is the correct upgrade — it adds organic vapor coverage without changing the respirator platform or connection system. Do not use the 7582P100L in organic vapor environments; the acid gas sorbent alone does not capture solvent vapors.

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Honeywell North 7582P100L — Acid Gas + P100 (OV/P100 with acid gas emphasis, no dedicated OV layer):

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Honeywell North 7583P100L — OV + Acid Gas + P100:

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7582P100L vs 7583P100L at a Glance

Specification	7582P100L	7583P100L
Cartridge Type	Combination — Acid Gas + P100	Combination — OV + Acid Gas + P100
NIOSH Class	OV / AG / P100	OV / AG / P100
Organic Vapor	Limited (nuisance-level only per NIOSH designation)	Full OV protection
Acid Gas (Cl₂, HCl, SO₂)	Yes — primary protection class	Yes — full AG protection
Particulate (P100)	Yes — ≥99.97%	Yes — ≥99.97%
Ammonia / Methylamine	No	No
Connection System	North bayonet (proprietary)	North bayonet (proprietary)
Compatible Respirators	North 5500, 7700, 5400, 7600 series only	North 5500, 7700, 5400, 7600 series only
Best For	Acid gas + particulate; no confirmed OV	Mixed OV + acid gas + particulate environments
Price Tier	Mid — lower than 7583P100L	Mid-high — premium for added OV layer

Product Profiles

Honeywell North 7582P100L

The 7582P100L is a NIOSH-approved combination cartridge for acid gas and P100 particulate protection. It covers acid gases including chlorine (Cl₂), hydrogen chloride (HCl), and sulfur dioxide (SO₂), while the integrated P100 layer filters ≥99.97% of oil and non-oil aerosols. The North bayonet mount fits all four North facepiece series — the 5500 and 7700 half-face masks and the 5400 and 7600 full-face respirators. It is sold as a pair. The 7582P100L is the right choice when your hazard profile is acid gas and particulate with no confirmed organic vapor — stepping up to the 7583P100L for an environment where organic vapors are also documented is not overcaution; it is a NIOSH compliance requirement.

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Honeywell North 7583P100L

The 7583P100L is the broader combination cartridge in the North 75-series — it adds a dedicated organic vapor sorbent layer to the acid gas and P100 protection already present in the 7582P100L. This three-class NIOSH approval (OV + AG + P100) makes the 7583P100L the go-to cartridge for environments where solvents, paint vapors, or other organic compounds are confirmed alongside acid gases and airborne particulate. Same North bayonet platform, same facepiece compatibility, same sold-as-a-pair format — the only difference is the additional OV protection layer, which comes at a modest price premium. Do not use the 7582P100L as a substitute in organic vapor environments; if OV is present, the 7583P100L is the correct specification.

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What Each Cartridge Protects Against

Hazard	7582P100L	7583P100L
Chlorine (Cl₂)	✅ AG	✅ AG
Hydrogen chloride (HCl)	✅ AG	✅ AG
Sulfur dioxide (SO₂)	✅ AG	✅ AG
Organic vapors — solvents (toluene, xylene, hexane, MEK, esters, alcohols)	❌ No dedicated OV layer	✅ Full OV layer
Paint vapors / coating solvents	❌ Not rated	✅ OV layer
Dust, mist, fume (non-oil & oil aerosols)	✅ P100 (≥99.97%)	✅ P100 (≥99.97%)
Welding fumes (particulate component)	✅ P100	✅ P100
Silica dust	✅ P100	✅ P100
Ammonia / methylamine	❌ No	❌ No
Mercury vapor	❌ No	❌ No
Carbon monoxide (CO)	❌ No	❌ No
Oxygen deficiency	❌ No — SCBA required	❌ No — SCBA required

Key Differences

Organic Vapor Protection: The One Real Difference

The entire decision between these two cartridges rests on one question: is organic vapor confirmed in your hazard environment? The 7583P100L carries a full NIOSH-approved organic vapor sorbent layer — activated carbon media engineered to capture solvent vapors including toluene, xylene, hexane, MEK, acetone, and a broad range of esters and alcohols. The 7582P100L does not carry an equivalent dedicated OV layer. Both cartridges share the same acid gas and P100 protection. If organic vapor is not documented in your hazard assessment, the 7582P100L is the leaner, lower-cost choice. If it is, the 7583P100L is the only compliant option. Review your SDS documentation and consult the cartridge selection guide before locking in an order.

Cost vs Coverage Trade-Off

The 7583P100L carries a modest price premium over the 7582P100L — the cost of the additional organic vapor sorbent media. For workplaces where acid gas and particulate are the documented hazards and organic vapor is genuinely absent, ordering the 7583P100L does not add meaningful safety margin; it adds cost and slightly more breathing resistance from the additional sorbent layer. For workplaces with any confirmed organic vapor presence, the 7583P100L is the correct cartridge regardless of the cost difference — using the 7582P100L in an OV environment is a compliance failure, not a cost saving. See the respirator filter types explained guide for how NIOSH classification works.

Cartridge Change-Out Scheduling

Both cartridges require a written change-out schedule under OSHA 1910.134 — neither has a visual end-of-service-life indicator (ESLI) for the gas/vapor layer. For the 7582P100L, the change-out interval is driven by acid gas concentration and exposure time. For the 7583P100L, the OV sorbent layer is typically the limiting component — organic vapor sorbents saturate based on vapor concentration, humidity, and exposure duration. In high-humidity or high-concentration environments, the 7583P100L may require more frequent change-outs than the 7582P100L in an equivalent acid gas task. Consult the respirator cartridge color chart guide for NIOSH color code reference and review the manufacturer's change-out schedule calculator for your specific exposure conditions.

Sorbent Layer Architecture

The 7582P100L uses a combination sorbent optimized for acid gas capture — typically a combination of activated carbon impregnated with specific reagents effective against chlorine, HCl, and SO₂. The 7583P100L adds a larger activated carbon bed for broad organic vapor capture on top of that acid gas sorbent. The result is a physically larger cartridge with slightly more airflow resistance. In practice, the difference in breathing resistance between the two cartridges is small, but workers in physically demanding tasks may notice it over a full shift. Both cartridges are appropriate for half-face (5500/7700) and full-face (5400/7600) North respirators. For background on how OV cartridge selection works in North platform respirators, see the Honeywell North cartridge guide.

Application Specificity vs Flexibility

The 7582P100L is a more targeted cartridge — correct for acid gas + particulate environments and unnecessary (or under-specified) anywhere else. The 7583P100L is the more flexible choice: it covers the 7582P100L's hazard profile entirely, plus adds organic vapor protection. In environments where hazard conditions shift between tasks or where workers move between acid gas and organic vapor work areas in the same shift, the 7583P100L's broader coverage profile reduces the risk of cartridge mismatch. For workplaces with rigidly defined, single-hazard environments, the 7582P100L remains the leaner specification. For everything else, the 7583P100L removes ambiguity. Browse both in the Honeywell North respirator filters and cartridges collection.

Which Should You Buy?

Buy the 7582P100L if…

• Your hazard assessment confirms acid gas only (chlorine, HCl, SO₂) with no documented organic vapor presence.
• You work in water treatment, chemical plant maintenance, or industrial cleaning where acid gases and particulate — not solvents — are the primary hazards.
• You want the most cost-effective cartridge for a pure acid gas + particulate profile without paying for OV coverage you do not need.
• Your SDS documents confirm no organic vapor co-exposure in your specific work area or task.
• You already own a Honeywell North 5500, 7700, 5400, or 7600 series respirator and need acid gas + P100 combination protection.

Buy the 7583P100L if…

• Your environment has both organic vapor and acid gas present alongside particulate — such as auto body shops using acid-catalyzed coatings, industrial spray painting near acid gas sources, or chemical facilities handling both solvents and acid chemicals in the same work area.
• You work with acid-catalyzed coatings, two-component lacquers with acid hardeners, or solvent-based strippers that also generate acid vapors.
• Your hazard conditions shift or are not precisely characterized — the 7583P100L's broader OV coverage provides margin when exposure profiles are variable.
• You need a single-cartridge solution for multi-hazard environments to simplify your cartridge inventory and change-out tracking.
• Your SDS or industrial hygiene sampling shows solvent vapors alongside acid gas in your breathing zone, making the 7583P100L the only compliant option under OSHA 1910.134 for that environment.

Best Applications by Use Case

Water Treatment and Chlorination (7582P100L)

Water treatment workers handling chlorine gas for disinfection, or maintenance crews working near chlorination equipment, face a primary acid gas hazard with minimal organic vapor risk. The 7582P100L's acid gas + P100 combination directly addresses this profile — the acid gas layer covers chlorine and any HCl or SO₂ generated as byproducts, while the P100 layer handles chemical dust and aerosol from handling chlorination compounds. This is the most common specification for water and wastewater utility respirator programs on North-platform facepieces. For particulate-only adjacent tasks, the 7580P100 P100 filter is the paired lower-cost option when acid gas is absent.

Auto Body and Acid-Catalyzed Coatings (7583P100L)

Auto body shops applying acid-catalyzed primers, two-component clearcoats, or isocyanate-hardener systems expose workers to both organic solvent vapors from the coating carrier and acid gas byproducts from the catalyst. This is the textbook application for the 7583P100L — the integrated OV layer captures solvent vapors while the acid gas layer addresses the acid catalyst off-gas, and the P100 handles overspray particulate. Using only the 7582P100L in this environment would leave the organic vapor hazard unaddressed. See the organic vapor vs P100 guide for how the OV and particulate layers interact in spray coating applications.

Chemical and Industrial Laboratories (7582P100L or 7583P100L)

Laboratory selection depends on the reagents in use. If the lab work involves acid reagents — HCl, H₂SO₄, formaldehyde fixatives — without organic solvent exposure, the 7582P100L matches the profile. If the same shift involves solvent handling (hexane, acetone, ethanol, toluene) in addition to acid reagents, the 7583P100L is the correct specification. Many industrial hygiene programs default to the 7583P100L in general laboratory settings precisely because reagent exposure can shift from task to task within a single shift. Confirm your specific reagents against the cartridge's NIOSH approval before finalizing the selection. The respirator filter types explained guide covers how NIOSH combination classes are determined.

Chemical Plant Maintenance (7583P100L)

Chemical plant environments routinely co-present organic vapors and acid gases from process equipment, reaction vessels, and cleaning operations. A maintenance technician moving between a solvent degreasing operation and an acid gas atmosphere in the same shift needs the 7583P100L's combined OV + acid gas + P100 coverage. The 7582P100L alone would be compliant only in the acid gas sections of the plant. For environments that also add ammonia or methylamine to the hazard mix, step up to the 75SCP100L multi-contaminant cartridge.

Industrial Cleaning and Surface Treatment (7582P100L or 7583P100L)

Acid-based industrial cleaning — descaling, metal surface treatment, disinfection with chlorinated compounds — generates acid gas vapors and aerosol without necessarily involving organic solvents. The 7582P100L covers this profile cleanly. If the cleaning process uses solvent-based degreasers or strippers in the same work area or shift, the 7583P100L is required. Review the SDS for each cleaning product involved to confirm which hazard classes are present before selecting a cartridge. Consult the how to choose a respirator cartridge guide for a decision framework built around SDS hazard data.

Respirator Compatibility

Both the 7582P100L and 7583P100L use the Honeywell North bayonet connection — a proprietary mount that fits all Honeywell North facepieces in the 5500, 7700, 5400, and 7600 series. This bayonet system is mechanically incompatible with 3M bayonet, Moldex bayonet, and all other brands. Do not attempt to use North cartridges on non-North facepieces.

Respirator Series	Fits 7582P100L	Fits 7583P100L	Type
Honeywell North 5500 series	✅	✅	Half-face respirator
Honeywell North 7700 series	✅	✅	Half-face respirator
Honeywell North 5400 series	✅	✅	Full-face respirator
Honeywell North 7600 series	✅	✅	Full-face respirator
3M 6000, 6500, 7500, 7800S series	❌	❌	Incompatible — different bayonet
Moldex, GVS, MSA, or any other brand	❌	❌	Incompatible — different connection

If you run a 3M facepiece and need OV + acid gas + P100 coverage, the equivalent 3M combination cartridge is the 3M 60923 (OV/AG/P100). For OV + P100 on a 3M platform without acid gas, use the 3M 60921. For acid gas + P100 without OV on a 3M platform, the acid gas combination option is the 3M 60923 (or the 3M 6003 gas-only with a separate 3M 2091 P100 filter stacked). For 3M cartridge selection, see the 3M filter cartridge guide.

Related Guides

• Honeywell North Cartridge Guide — full 75-series cartridge lineup with selection decision tree
• How to Choose a Respirator Cartridge — NIOSH class selection framework for any work environment
• Respirator Filter Types Explained — OV, AG, P100, N95, R95 defined and compared
• Organic Vapor vs P100 — when you need OV, when you need P100, and when you need both
• Respirator Cartridge Color Chart — NIOSH color code reference for all cartridge classes
• 3M Filter Cartridge Guide — 3M equivalent cartridge selection if you run a 3M facepiece
• P100 vs N95: Which Do You Need? — particulate class comparison and selection guidance

Frequently Asked Questions

What is the difference between the 7582P100L and 7583P100L?

The 7583P100L adds a dedicated organic vapor (OV) sorbent layer that the 7582P100L does not have. Both cartridges cover acid gas (Cl₂, HCl, SO₂) and P100 particulate. The 7583P100L is the correct choice wherever solvents, paint vapors, or other organic vapors are present alongside acid gas. If organic vapor is genuinely absent from your hazard assessment, the 7582P100L is the leaner, more cost-effective specification. See the cartridge selection guide for the full decision framework.

Can I use the 7582P100L in an auto body shop?

Only if your hazard assessment confirms no organic vapor is present — which is rare in auto body environments. Most auto body work involving primers, clearcoats, or two-component coatings generates organic solvent vapors alongside any acid catalyst off-gas. In that environment, the 7583P100L is the correct specification because it adds the organic vapor layer the 7582P100L lacks. Using only the 7582P100L in an OV environment is a NIOSH compliance gap.

Are the 7582P100L and 7583P100L interchangeable on the same respirator?

They use the same North bayonet connection and fit the same facepieces — North 5500, 7700, 5400, and 7600 series. Mechanically, either cartridge mounts on any of those facepieces. However, they are not interchangeable from a protection standpoint: substituting the 7582P100L for the 7583P100L in an organic vapor environment leaves the OV hazard unaddressed. Always match the cartridge to the hazard assessment, not just the facepiece. The Honeywell North cartridge guide covers how to map the full 75-series lineup to hazard classes.

Does the 7582P100L protect against organic vapors at all?

The 7582P100L carries an OV component in its NIOSH designation, but its protection emphasis is acid gas. It is not the correct cartridge for environments where organic vapor is a confirmed primary hazard — that requires the 7583P100L (OV + AG + P100) or the 7581P100L (OV + P100, no acid gas). Do not use the 7582P100L as an organic vapor cartridge in solvent-heavy environments. Review the organic vapor vs P100 guide for the protection class distinctions.

What respirators are compatible with both cartridges?

Both the 7582P100L and 7583P100L use the Honeywell North bayonet connection and are compatible with all four North facepiece series: the 5500 and 7700 half-face respirators, and the 5400 and 7600 full-face respirators. They are not compatible with any 3M, Moldex, MSA, GVS, or other brand facepiece — the North bayonet mount is proprietary and mechanically incompatible with other bayonet systems. Browse compatible North facepiece options in the Honeywell North respirator filters and cartridges collection.

How often do I need to change out these cartridges?

Both cartridges require a written change-out schedule per OSHA 1910.134 — neither has a visual end-of-service-life indicator (ESLI) for the gas/vapor layer. Change-out frequency depends on contaminant concentration, exposure duration, temperature, humidity, and breathing rate. For the 7582P100L, the acid gas layer is typically the limiting factor. For the 7583P100L, the OV sorbent layer is often more sensitive to humidity and concentration. Follow the manufacturer's change-out schedule calculator and document intervals in your written respiratory protection program. The respirator cartridge color chart guide provides additional context on cartridge service life by class.

Which cartridge is better for paint spraying?

For most paint spraying work — including solvent-based coatings, lacquers, and two-component systems — the 7583P100L is the correct choice because it covers the organic solvent vapors in the coating carrier alongside any acid catalyst off-gas and paint overspray particulate. The 7582P100L is not suitable for solvent-based coating work. If your coating is water-based with no acid catalyst and no organic vapor, the 7580P100 P100 filter or 7581P100L (OV + P100) may be the more precise specification.

Does the 7583P100L protect against silica dust?

Yes — the integrated P100 layer in the 7583P100L (≥99.97% filtration efficiency) captures respirable crystalline silica (RCS) particles. If your environment combines organic vapor, acid gas, and silica dust exposure — such as certain abrasive blasting or surface preparation tasks — the 7583P100L covers all three hazard classes in one cartridge. Confirm that no additional hazard classes (ammonia, mercury vapor) are present before relying on the 7583P100L as a complete solution. For silica-specific guidance, see the best respirator for silica dust guide.

Is the 7583P100L worth the extra cost over the 7582P100L?

Only if organic vapor is confirmed in your hazard environment. If your SDS documentation and hazard assessment support acid gas and particulate only — with no organic vapor — the 7582P100L is the correct specification and the price premium for the 7583P100L provides no additional protection benefit. If organic vapor is present, the 7583P100L is not optional — it is the compliance-correct cartridge, and the cost difference is irrelevant to the safety decision. Do not substitute a lower-cost cartridge to save money when the hazard requires the broader-class option. The respirator filter types explained guide covers how NIOSH protection classes are determined.

Can these cartridges be used with 3M respirators?

No. The 7582P100L and 7583P100L both use the Honeywell North bayonet connection, which is mechanically incompatible with 3M's bayonet system. If you own a 3M respirator and need OV + acid gas + P100 coverage, the equivalent 3M cartridge is the 3M 60923 (OV/AG/P100). See the 3M filter cartridge guide for the complete 3M lineup and equivalent cartridge mappings.

What is the NIOSH approval number for the 7582P100L and 7583P100L?

Both the 7582P100L and 7583P100L are NIOSH-approved combination cartridges in the OV/AG/P100 classification. NIOSH TC approval numbers for Honeywell North 75-series cartridges are documented on the product packaging and in the official NIOSH NPPTL certified equipment list. Always verify the current approval number on the cartridge label against the NIOSH database before issuing for use in a respiratory protection program. For background on NIOSH classification codes, see the respirator filter types explained guide.

What is the closest alternative to the 7583P100L if it is out of stock?

Within the Honeywell North 75-series platform, the 75SCP100L multi-contaminant P100 cartridge offers the broadest coverage including OV, acid gas, ammonia, and P100 — a step up in protection scope. If you are running a 3M respirator, the 3M 60923 is the cross-brand equivalent for OV + AG + P100. Do not substitute the 7582P100L as an alternative to the 7583P100L in organic vapor environments — that is a downgrade in protection, not a substitution. Browse the full Honeywell North collection for availability.

What is the difference between the 7581P100L, 7582P100L, and 7583P100L?

All three are North 75-series P100 combination cartridges with different gas/vapor protection classes. The 7581P100L covers organic vapor + P100 (no acid gas). The 7582P100L covers acid gas + P100 (acid gas emphasis, limited OV). The 7583P100L covers organic vapor + acid gas + P100 — the broadest of the three. Choose the 7581P100L for OV-only environments, the 7582P100L for acid gas + particulate without OV, and the 7583P100L when both OV and acid gas are confirmed present. The Honeywell North cartridge guide covers the full 75-series comparison in detail.

Do these cartridges protect against welding fumes?

The P100 layer in both cartridges captures the metal oxide particulate component of welding fumes at ≥99.97% efficiency. However, welding also generates gaseous hazards — ozone, nitrogen oxides, carbon monoxide — that neither the 7582P100L nor the 7583P100L are rated to capture. For welding applications, confirm the specific fume composition from your SDS and welding process documentation before relying on either cartridge as a complete solution. The best respirator for welding fumes guide covers the full cartridge selection decision for welding environments.

How do I know if I need the 7582P100L or 7583P100L for my job?

Start with your SDS documents and site-specific hazard assessment. Identify every airborne hazard class present in your breathing zone: if the list includes organic vapor alongside acid gas and particulate, the 7583P100L is required. If organic vapor is absent and only acid gas and particulate are documented, the 7582P100L is the leaner correct choice. If neither cartridge covers all your documented hazards (e.g., ammonia is also present), step up to the 75SCP100L multi-contaminant cartridge. For a structured decision process, use the how to choose a respirator cartridge guide.