Honeywell North Cartridge Guide: Complete Selection Hub (2026)

Honeywell North Cartridge Guide

Honeywell North respirator cartridges are engineered for the North 5500, 7700, 5400, and 7600 series respirators — they are NOT cross-compatible with 3M, Moldex, or MSA products. This guide covers every North cartridge family, selection by hazard type, prefilter options, and head-to-head comparisons with 3M equivalents. Browse the complete North respirator filters & cartridges collection or use the hazard lookup below.

Quick picks: P100 only → North 7580 P100. OV/P100 → North 7581P100L. OV/AG/P100 → North 7583P100L. Multi-gas/P100 → North 75SCP100L. See the best North cartridges guide for full ranked picks.

North Cartridge Families: N-Series vs 75-Series

North cartridges divide into two main families:

• 75-Series combination cartridges — include integrated P100 filtration plus gas/vapor sorbent: 7581P100L OV/P100, 7582P100L AG/P100, 7583P100L OV/AG/P100, 7584P100L Ammonia/P100, 75SCP100L multi-gas/P100. The most versatile for mixed-hazard environments.
• N-Series gas-only cartridges — chemical sorbent only, no P100: N75001L OV, N75002L AG, N75003L OV/AG, N75004L Ammonia. Use when particulate hazards are absent.
• Stand-alone P100 filters — particulate only: 7580 P100 cartridge, 75FFP100 flat filter.
• Multi-gas cartridge (no P100) — 75SCL Defender covers OV, AG, ammonia, and inorganic gases without integrated P100.

P100 Cartridges and Filters

For a guided comparison of North P100 options, see best North cartridge for silica dust and best North cartridge for welding.

OV, Acid Gas, and Multi-Gas Cartridges

Prefilters: N95, R95, N99 Options

North prefilters are thin filter pads designed to add particulate protection to gas cartridges or to use as standalone particulate filters in low-filtration configurations. Available ratings: 7506N95 prefilter (N95, not oil-resistant), 7506R95 prefilter (R95, oil-resistant 8 hours). For environments requiring P100 efficiency, use the full 7580 P100 cartridge or a 75-series combination cartridge instead.

Respirator Compatibility

• North 5500 series half-mask — accepts N-series and 75-series cartridges
• North 7700 series half-mask — accepts N-series and 75-series cartridges
• North 7600 series full-face — accepts 75-series combination cartridges; verify per model

Cross-brand warning: North cartridges physically appear to engage with some 3M respirators but the seal is not validated and may leak. Never use North cartridges on non-North respirators.

Honeywell North vs 3M Cartridge Comparison

North and 3M produce near-equivalent combination cartridges across all hazard classes. Key head-to-head comparisons:

• North 7581P100L vs 3M 60921 — OV/P100 comparison
• North 7583P100L vs 3M 60923 — OV/AG/P100 comparison
• North 75SCL vs 3M 6006 — multi-gas (no P100)
• North 75SCL vs 3M 60926 — multi-gas + P100

Honeywell North Cartridge FAQ

What respirators are compatible with Honeywell North cartridges?

Honeywell North cartridges fit only North-brand respirators with the North bayonet mount: the 5500 series half-mask, 7700 series half-mask, 5400 series full-face, and 7600 series full-face. North cartridges are NOT compatible with 3M, Moldex, MSA, or any other brand. See North half-mask collection and North full-face collection.

What is the difference between North N-series and 75-series cartridges?

North cartridges divide into two families by mount type and compatible respirator. The 75-series (7580P100, 7581P100L, 75SCL, 75SCP100L, 75FFP100, 7582P100L, 7583P100L, 7584P100L) fit the 5500 half-mask and 7700 series. The N-series (N75001L, N75002L, N75003L, N75004L) are lower-profile cartridges for specific North half-mask platforms. Always verify compatibility against your specific respirator model — not all North cartridges fit all North respirators.

What is the Honeywell North 7583P100L used for?

The North 7583P100L is a combination organic vapor + acid gas + P100 cartridge — the most comprehensive single-cartridge protection in the North lineup. It covers OV hazards (solvents, petroleum vapors), acid gas hazards (HCl, SO2, HF), and P100 particulate filtration (≥99.97% efficiency, oil-proof). Ideal for chemical plant, pharmaceutical, and multi-hazard industrial environments. See the 7583P100L full review and 7583P100L vs 3M 60923 comparison.

What is the difference between the North 75SCL and 75SCP100L?

The 75SCL is the North Defender multi-gas/vapor cartridge without integrated P100 filtration — covers OV, AG, ammonia, and inorganic gases. The 75SCP100L is the multi-contaminant version WITH integrated P100 filter, providing both chemical and particulate protection. Use the 75SCL when particulate hazards are absent or managed separately; use the 75SCP100L when both chemical and particulate protection are needed simultaneously. See 75SCL vs 75SCP100L comparison.

What is the Honeywell North 7580 P100 used for?

The North 7580 P100 is a standalone P100 particulate filter cartridge — no gas/vapor protection. It is the North equivalent of the 3M 2091. Use it for: metallic fumes, welding particulate, lead dust, silica dust, asbestos (when gas hazards are absent). It is NOT appropriate when organic vapor or gas hazards are present alongside particulate. See the 7580 P100 review and best North cartridge for silica dust.

Does the North 75FFP100 provide the same protection as the 7580 P100?

Yes — the North 75FFP100 and the 7580 P100 both provide P100 particulate filtration (≥99.97% efficiency, oil-proof). The difference is form factor: the 75FFP100 is a flat disc filter designed for different mounting configurations or stacking on gas cartridges, while the 7580 P100 is a standalone cartridge-style filter. Both protect against the same particulate hazards. See the 75FFP100 review.

Can I use North prefilters (7506) with existing cartridges?

North prefilters (7506N95, 7506R95) are thin filter pads designed to be used in front of gas cartridges to add particulate filtration without replacing the cartridge. They are appropriate when you want to add particulate protection to a gas-only cartridge. However, for most industrial applications, a combination cartridge (7581P100L OV/P100, 7583P100L OV/AG/P100) provides cleaner integrated protection.

How does the North cartridge compare to the 3M 60923?

The North 7583P100L and the 3M 60923 are both OV/AG/P100 combination cartridges — the most direct comparison in the two catalogs. Both provide P100 particulate + OV + acid gas protection. Key differences: mount compatibility (North 7583P100L fits only North respirators; 3M 60923 fits only 3M 6000/7000/7800S/FF-400 series); service life per manufacturer data sheets; physical form factor. See the 7583P100L vs 3M 60923 head-to-head comparison.

What North cartridge should I use for paint spray finishing?

Spray painting requires OV/P100 protection (organic vapor for solvent vapors + P100 for paint aerosol particulate). The North 7581P100L OV/P100 is the standard choice for spray painting and surface finishing in North respirator users. See the best North cartridge for paint fumes guide.

What North cartridge do I use for ammonia?

Standard OV cartridges do not protect against ammonia. Use the North 75SCL Defender (multi-gas, covers ammonia + inorganic gases) or the North 75SCP100L (multi-contaminant + P100 if particulate also present). See best North cartridge for ammonia guide.

How do I know which North cartridge fits my respirator model?

North cartridge compatibility is model-specific. The 7700 series and 5500 series half-masks accept the 75-series and N-series cartridges. Full-face 7600 series accepts 75-series combination cartridges. Always verify against the specific respirator model's user instructions or the Honeywell North compatibility chart before ordering. Cartridge product pages on WC Safety list compatible respirator models.

Is the North 75SCL the same as a multi-gas/vapor cartridge?

Yes — the North 75SCL Defender is a multi-gas/vapor (MGVP) cartridge without integrated P100. It covers organic vapors, acid gases, ammonia/methylamine, chlorine, and inorganic gases. It does NOT include P100 particulate filtration (use the 75SCP100L for combined chemical + P100 protection). Compare: 75SCL vs 3M 6006 comparison and 75SCL vs 3M 60926 comparison.

What North cartridge should I use for mold remediation?

Mold remediation requires P100 particulate protection for mold spores. Some remediation environments also have chemical off-gassing requiring OV or MGVP protection. For mold particulate only: North 7580 P100. For mold + chemical vapors: North 7583P100L OV/AG/P100. See best North cartridge for mold remediation guide.

Are North cartridges available without P100 filtration?

Yes. N-series cartridges (N75001L OV, N75002L AG, N75003L OV/AG, N75004L Ammonia) and the 75SCL are gas/vapor-only cartridges without integrated P100. Use these when particulate hazards are absent. When particulate hazards are also present, the 75-series combination cartridges (7581P100L, 7582P100L, 7583P100L, 75SCP100L) are the appropriate choice.

Where can I buy Honeywell North respirator cartridges?

North cartridges are stocked in the Honeywell North respirator filters & cartridges collection at WC Safety. See the best North cartridges guide for the top picks by hazard type, including paint, welding, chemical, and multi-gas scenarios.