Honeywell North 75SCL vs 3M 60926: Multi-Gas Cartridge Comparison

By the WC Safety Editorial Team — Last updated: 2026.

Short Answer

Choose the Honeywell North 75SCL if you use Honeywell North respirators and need gas-only multi-gas protection. Choose the 3M 60926 if you use 3M bayonet respirators and need multi-gas protection with a P100 particulate filter. Do not mix brands. These two cartridges are not interchangeable: each fits only its own brand of facepiece. Once you know which respirator you own, the second question is whether particulates are present — the 3M 60926 includes a P100 particulate filter, while the Honeywell North 75SCL is gas-and-vapor only. For the wider lineups, see the Honeywell North cartridge guide and the 3M cartridge guide.

Specs: Honeywell North 75SCL — SKU 75SCL, GTIN 0883940107622 (multi-gas, gas-only, North bayonet). 3M 60926 — SKU 60926, GTIN 50051138541878 (multi-gas + P100 particulate filter, 3M bayonet).

Quick Comparison Table

Compatibility Comes First

Before you compare a single contaminant, settle the only question that can make a cartridge useless: does it fit your respirator? Honeywell North cartridges fit Honeywell North facepieces. 3M bayonet cartridges fit 3M bayonet facepieces. They are not cross-compatible, and the two bayonet systems are physically different — a Honeywell North 75SCL will not seat on a 3M facepiece, and a 3M 60926 will not seat on a Honeywell North facepiece. Never force a cartridge that does not belong, because a connection that is not a sealed, approved match is not protection at all.

This is why you should not buy on contaminant class alone. Two cartridges can carry similar gas chemistry and still be the wrong purchase if they do not match the respirator hanging in your locker. Decide the brand first, by the facepiece you already own, then choose the cartridge within that brand. If you run Honeywell North half mask respirators (such as the North 5500 or 7700) or full face respirators (such as the North 5400 or 7600), you are in the Honeywell North system. If you run 3M 6000, 6500 or 7500 series respirators, you are in the 3M system.

Protection Difference

Once compatibility is settled, the protection difference is straightforward. The Honeywell North 75SCL is a multi-gas and vapor cartridge with no particulate filter. It covers organic vapor, acid gas, ammonia, methylamine and formaldehyde, but it does nothing against particles. The 3M 60926 is a multi-gas and vapor cartridge with a bonded P100 particulate filter, so it covers a comparable gas range and adds particulate protection that captures at least 99.97% of airborne particles and is oil-proof.

So the practical rule is this: if particles, dust, mold, spray aerosol, or welding fume may be present, the P100 particulate filter matters, and on a 3M respirator the 60926 delivers it. If the air holds only gases and vapors, the 75SCL covers the chemistry on a Honeywell North respirator without the added filter. Note the asymmetry this comparison creates: the closest Honeywell North match to the 3M 60926 is not the gas-only 75SCL at all — it is the Honeywell North 75SCP100L, which adds a P100 particulate filter to the same multi-gas chemistry. For a refresher on classes and colors, see how to choose a respirator cartridge and the respirator cartridge color chart.

When the Honeywell North 75SCL Is the Better Choice

• You already run Honeywell North respirators — the North 5500, 7700, 5400 or 7600 — so the 75SCL is the cartridge that fits your facepiece.
• Gas-only environments, where the exposure is vapor and gas with no particulates.
• Lower breathing resistance is a priority for long shifts or high exertion, and particulates are confirmed absent.
• Chemical handling without particulate, such as decanting and mixing volatile chemicals in clean indoor settings.
• You are standardized on the North cartridge ecosystem for stocking and replacement. See the Honeywell North 75SCL review and browse Honeywell North respirator filters and cartridges.

When the 3M 60926 Is the Better Choice

• You already run 3M respirators — the 3M 6000, 6500 or 7500 series, or a 3M full face respirator — so the 60926 is the cartridge that fits your facepiece.
• You need multi-gas plus a P100 particulate filter in one cartridge.
• Dust, mist, aerosol, spray, mold, or other particulate shares the air with gases and vapors.
• You are standardized on the 3M cartridge ecosystem. See the 3M 60926 review, the 3M cartridge guide, and browse 3M respirator filters and cartridges.

Which One Is Easier to Breathe Through?

The Honeywell North 75SCL. A gas-only cartridge presents a single obstacle to each breath — the sorbent bed — while the 3M 60926 adds a P100 particulate filter in series with its sorbent, so air passes through more media. More media means more breathing resistance, and the 75SCL is the easier-breathing cartridge as a result. That said, breathing comfort is not a reason to skip particulate protection you actually need. If your air contains dust or mist, the 60926's added resistance is simply the price of filtering it; choosing the gas-only cartridge to breathe easier would leave those particles unfiltered.

Which One Should You Buy?

Buy the Honeywell North 75SCL if you run Honeywell North respirators and your exposure is gas and vapor only. It fits your North facepieces, covers the multi-gas chemistry, and breathes easier than a combination cartridge.

Buy the 3M 60926 if you run 3M bayonet respirators and need multi-gas protection with a P100 particulate filter. It fits your 3M facepieces and covers both the gas and the particulate hazard in one cartridge.

Do not buy either if the concentration is unknown, or the atmosphere is IDLH, oxygen-deficient, or otherwise requires supplied air or an SCBA. Air-purifying cartridges only protect against known contaminants at known concentrations in atmospheres with adequate oxygen. Base the decision on a documented exposure assessment, and confirm fit testing and medical evaluation for the respirator you use.

Related Guides

• Honeywell North cartridge guide and the 3M cartridge guide.
• How to choose a respirator cartridge and the respirator cartridge color chart.
• Honeywell North 75SCL and its 75SCL review.
• 3M 60926 and its 60926 review.
• Browse Honeywell North filters and cartridges and 3M filters and cartridges.

FAQs

Safety note: Cartridge selection depends on the specific contaminant, its airborne concentration, and the oxygen level, under applicable OSHA and NIOSH requirements including fit testing and medical evaluation. This guide is for research and does not replace a workplace hazard assessment. Never use air-purifying cartridges in oxygen-deficient or IDLH atmospheres.