Honeywell 7581 vs 7582 vs 7583 P100L Cartridge: Three-Way Comparison

honeywell 7581 vs 7582 vs 7583: the short answer

Short answer: The Honeywell North 7580-series P100L combination cartridges share the same NIOSH-approved P100 particulate filter — rated at 99.97% filtration efficiency against 0.3-micron particles — but differ in the chemical vapor protection layered on top of that filter. Selecting the wrong cartridge does not change the particulate protection you receive, but it leaves a gap in vapor or gas coverage that can

Honeywell North 7581 vs 7582 vs 7583 P100L: Which Combination Cartridge Matches Your Chemical Hazard Profile?

Published May 18, 2026 · Last updated July 27, 2026

The Honeywell North 7580-series P100L combination cartridges share the same NIOSH-approved P100 particulate filter — rated at 99.97% filtration efficiency against 0.3-micron particles — but differ in the chemical vapor protection layered on top of that filter. Selecting the wrong cartridge does not change the particulate protection you receive, but it leaves a gap in vapor or gas coverage that can result in overexposure to inhalation hazards not covered by your cartridge. This three-way guide explains precisely what each cartridge covers, how to read your Safety Data Sheet (SDS) to choose correctly, and what NIOSH approval means for each model.

Quick-Reference Decision Table

North 7581 vs 7582 vs 7583 P100: Side by Side

Core fact: The 7581 is P100 plus organic vapor only. The 7582 is P100 plus acid gas only, with no organic vapor coverage. The 7583 combines organic vapor, acid gas (HCl, SO2, Cl2) and P100 — select it whenever your SDS Section 2 lists acid gas hazards alongside solvents. Decision is driven entirely by hazard type identified in your workplace SDS and industrial hygiene assessment.

What Is P100 Filtration and Why It Matters

P100 is a NIOSH filter class defined under 42 CFR Part 84. The "P" designates oil-proof — the filter maintains 99.97% minimum efficiency even in oil-aerosol environments such as metalworking fluid mist, oil-based paint spray, and oil mist from machining operations. P100 filters are color-coded magenta/purple on all NIOSH-approved respirators. All three cartridges in the 7580 series use identical P100 filter media — the chemical sorbent bed is the only variable between models.

Honeywell North 7581P100L: Organic Vapor Plus P100

The Honeywell North 7581P100L is NIOSH-approved for organic vapor plus P100 particulate filtration. The organic vapor sorbent covers a broad class of volatile organic compounds including acetone, toluene, xylene, methanol, isopropyl alcohol, and similar VOCs, subject to the vapor's boiling point, concentration, and warning properties per your SDS. The 7581P100L is not approved for acid gases (HCl, SO2, Cl2), mercury vapor, formaldehyde, or ammonia. If acid gases appear in your SDS Section 2 you need the 7582P100L or the 7583P100L; mercury vapor, formaldehyde and ammonia each require a different specialized cartridge that no 7580-series OV or acid gas cartridge provides.

Typical 7581P100L applications: automotive refinishing, industrial spray painting, fiberglass lamination, adhesive application, solvent-based coating work, woodworking with finish coats, parts cleaning with solvent, and general manufacturing with VOC exposure and particulate generation.

Shop respirator cartridges at WC Safety including the full Honeywell North 7580 series.

Honeywell North 7582P100L: Acid Gas Plus P100

The Honeywell North 7582P100L is an acid gas plus P100 combination cartridge. Its sorbent is approved for acid gases — chlorine, hydrogen chloride, sulfur dioxide, hydrogen fluoride and chlorine dioxide — and it carries no organic vapor approval. It is not an alternative to the 7581P100L: if solvents or other volatile organic compounds appear in your SDS Section 2, the 7582P100L does not protect against them. Choose the 7582P100L when the hazard is acid gas together with particulate and no organic vapor is present; choose the 7583P100L when organic vapor and acid gas occur together. Review the NIOSH approval documentation on your cartridge packaging to confirm the approved contaminant list and maximum use concentrations.

Honeywell North 7583P100L: OV Plus Acid Gas Plus P100

The Honeywell North 7583P100L is NIOSH-approved for organic vapor, acid gas (including hydrogen chloride, sulfur dioxide, and chlorine), and P100 particulate filtration. This is the broadest chemical protection in the 7580 series. Select the 7583P100L whenever your SDS identifies acid gas hazards alongside organic vapor or particulate exposures.

Typical 7583P100L applications: iron and steel foundry operations, chemical plant maintenance, battery charging areas (hydrogen gas and sulfuric acid mist), chlorination processes, metal pickling with hydrochloric acid, pulp and paper operations involving chlorine-based bleaching compounds, and welding or cutting on galvanized metals that may release chlorine-containing fumes.

The 7583P100L can be used anywhere the 7581P100L or 7582P100L would be used — it provides a superset of protection. Some facilities standardize on the 7583P100L to simplify cartridge inventory management. The trade-off is slightly higher breathing resistance and cost compared to OV-only cartridges.

Compatible Facepieces and Sizing

All 7580-series cartridges use the North bayonet mount and are designed for the Honeywell North 7700 series half-mask and Honeywell North 5500 series half-mask. The 7700 series is available in small, medium, and large. These cartridges are not cross-compatible with 3M, MSA, or Moldex facepieces — the North bayonet is proprietary to the North product line. Fit testing under OSHA 29 CFR 1910.134(f) is required before use in any mandatory respiratory protection program.

How to Use Your SDS to Select the Right Cartridge

OSHA 29 CFR 1910.134(d)(1)(iii) requires that respirator selection be based on hazards identified in the workplace. Your SDS is the starting point:

1. Review Section 2 (Hazard Identification) of each chemical SDS used in your work area.
2. Review Section 8 (Exposure Controls/Personal Protection) for recommended respirator type.
3. If acid gases (HCl, SO2, Cl2, HF) are listed on their own — select the 7582P100L. If acid gases are listed alongside organic vapor — select the 7583P100L.
4. If only organic vapor is listed — the 7581P100L is appropriate. The 7582P100L is not: it carries no organic vapor approval.
5. If concentrations exceed 10x the OSHA PEL or approach IDLH levels — consult your industrial hygienist. A supplied-air respirator may be required.

OSHA 29 CFR 1910.134 Compliance Requirements

Under OSHA 29 CFR 1910.134, any workplace requiring respirator use must maintain a written respiratory protection program covering: program administration, hazard-based cartridge selection, medical evaluation, annual fit testing, training, cartridge change schedules, and maintenance/storage procedures. Using any 7580-series cartridge without a documented written program and fit testing constitutes a violation of 1910.134.

Cartridge Change Schedule

Honeywell North does not publish a single service life figure because cartridge life depends on contaminant concentration, temperature, relative humidity, breathing rate, and work rate. OSHA 29 CFR 1910.134(d)(3)(iii) requires employers to establish a change schedule using objective data. Practical minimums: change at end of each shift if concentration is unknown; change immediately upon detecting odor breakthrough; change after any high-concentration emergency event; and never exceed the manufacturer's stated maximum service life if provided on the cartridge packaging.

Storage Best Practices

Store sealed 7580-series cartridges in original packaging in a cool, dry area away from chemical vapors. Activated carbon sorbent adsorbs ambient vapors even when not in use — exposure to storage-area chemicals reduces service life before the cartridge is ever used. Once opened, store cartridges in a sealed plastic bag between uses. Discard cartridges left unsealed overnight in a chemical environment.

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Primary sources for this page

The wording behind this page sits in OSHA 29 CFR 1910.134, NIOSH Certified Equipment List, OSHA 29 CFR 1910.132.

Why trust this page?

Why trust this page? Every figure on it is taken from the published text of the standard or the manufacturer document named beside it, not from a secondary summary. WC Safety is an independent PPE review site: we hold no inventory and sell nothing directly, so there is no product we need this page to favour. Where sources disagree, the page says so and plans on the more conservative figure rather than picking one.

Who wrote and reviewed this

By Steven Eaton, WC Safety Editorial. Reviewed against the primary sources cited on this page at each update. Steven Eaton is the editor of WC Safety and holds no safety certifications; this page reports what the standards say and is not a substitute for advice from a qualified professional on your specific exposure.

Methodology: how this page is maintained

Methodology. Figures are read from the primary source and re-checked whenever the underlying standard or a manufacturer document changes. No laboratory testing is performed for this page. Where a figure is not published, the page states that rather than estimating it, because a plausible invented number is more dangerous than an absent one.

Disclosure

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More questions on this topic

What is the difference between the 7581, 7582, and 7583?

7581=OV+P100. 7582=Acid Gas+P100, with no organic vapor coverage. 7583=OV+Acid Gas+P100. Choose by hazard type from your SDS.