Which Moldex cartridge is right for your hazard?

Best Moldex cartridge overall for most industrial hazards: the Moldex 7600 Smart Multi-Gas cartridge — NIOSH-approved, ESLI-equipped, and compatible with every Moldex 7000-series half-mask and 9000-series full-face respirator. If you need P100 particulate protection added, the Moldex 7667 Smart combination cartridge adds a pre-installed P100 filter. If your only hazard is organic vapor or acid gas at a known, monitored concentration, the Moldex 7300 OV+AG cartridge is the sharpest budget option on the platform. Browse the full Moldex respirator cartridges and filters collection for every available configuration.

Best Moldex Respirator Cartridges: Complete Buyer's Guide (2026)

The best Moldex respirator cartridges are not interchangeable — the right cartridge depends on which contaminant class you are actually exposed to, whether your program uses ESLI or a written change-out schedule, and whether you need particulate filtration added. Moldex's 7000-series cartridge platform covers six distinct hazard classes: organic vapor (OV), organic vapor plus acid gas (OV+AG), multi-gas Smart with end-of-service-life indicator (ESLI), P100 particulate filters, ammonia/methylamine, and combination cartridges that stack gas protection with P100 filtration in a single housing. All are NIOSH-approved under 42 CFR 84 and rated for use under OSHA 29 CFR 1910.134.

This guide ranks the seven best Moldex cartridges for 2026, matched to the hazards each addresses. Every product entry includes verified pricing, user ratings, a pros/cons breakdown, a dual purchase CTA, and clear notes on OSHA program implications. For the underlying hazard classification logic — when OV suffices vs. when you need OV+AG vs. when you need multi-gas — see our OV vs. OV+AG vs. multi-gas cartridge guide. For the ESLI vs. written schedule decision, see our ESLI vs. written change-out schedule guide.

Editorial verdict — best Moldex respirator cartridge overall: the Moldex 7600 Smart Multi-Gas+ESLI cartridge for programs relying on ESLI; the Moldex 7667 Smart combo where particulate protection is required alongside gas/vapor. Full rankings and pricing below.

Best Moldex cartridges 2026 — quick picks by category

1. Moldex 7600 Smart Multi-Gas Cartridge — Best overall Moldex cartridge

NIOSH class: OV/P100 + Acid Gases + Organic Vapor · ESLI: Yes · Price: $20.79/pair · Rating: 4.7/5

The Moldex 7600 Smart is the default best Moldex respirator cartridge for programs protecting against organic vapors, acid gases, and formaldehyde simultaneously. The "Smart" designation means the 7600 integrates Moldex's ESLI (End-of-Service-Life Indicator) — a color-changing chemical indicator strip visible on the cartridge face that turns from yellow-green to gray as the sorbent bed approaches saturation. This eliminates the administrative burden of a written change-out schedule for the contaminants the 7600 is approved against. Under OSHA 29 CFR 1910.134(d)(3)(iii)(B)(1), a NIOSH-approved ESLI is the explicit alternative to a written change-out schedule; the 7600 satisfies that requirement without additional industrial hygiene cost.

The 7600 protects against organic vapors, chlorine, hydrogen chloride, sulfur dioxide, hydrogen sulfide (escape), and formaldehyde. It does not include integrated P100 particulate filtration — for mixed gas/vapor and particulate hazards, step up to the Moldex 7667 Smart combo or mount the Moldex 7740+ IonicAir P100 filter on top of the 7600 using the platform's stacking system. For the direct cartridge-upgrade comparison, see our Moldex 7100 vs. 7300 vs. 7600 upgrade guide. Browse all options in the Moldex cartridges collection.

Related: ESLI vs. written change-out schedule — full compliance guide · Browse Moldex cartridges

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2. Moldex 7300 OV+AG Cartridge — Best budget Moldex cartridge

NIOSH class: OV + Acid Gas · ESLI: No · Price: $18.73/pair · Rating: 4.3/5

The Moldex 7300 is the correct budget Moldex cartridge for programs with a written change-out schedule that cover organic vapor plus acid gas at well-characterized concentrations. It is NIOSH-approved for organic vapors and acid gases including chlorine, hydrogen chloride, sulfur dioxide, and chlorine dioxide. The 7300 does not have ESLI; change-out timing must be determined by your industrial hygienist and documented in a written schedule under OSHA 1910.134(d)(3)(iii)(B)(2). It offers meaningfully better hazard coverage than the older 7100 (OV only) at the same price point — if your cartridge inventory still includes 7100s, the 7300 is the direct upgrade at no additional cost. See our Moldex 7100 vs. 7300 vs. 7600 upgrade guide for a full comparison.

The 7300 is the right choice when: (1) your SDS shows both organic vapors and acid gas hazards, (2) you have a documented written change-out schedule from a certified industrial hygienist, and (3) cost is a primary driver over the ESLI convenience premium. Programs without a written schedule should default to the Moldex 7600 Smart instead. The Moldex 7100 (OV only) is the correct step-down if acid gas is definitively absent; the 7300 covers both and should be preferred at identical pricing. See the full Moldex cartridges and filters collection.

Related: Moldex 7100 OV cartridge · OV vs. OV+AG vs. multi-gas selection guide

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3. Moldex 7740+ IonicAir P100 Particulate Filter — Best P100 filter on the Moldex platform

NIOSH class: P100 particulate (99.97%) · ESLI: N/A · Price: $21.19/pair · Rating: 4.6/5

The Moldex 7740+ IonicAir is the best P100 filter for the Moldex platform when particulate is the primary or sole inhalation hazard. The IonicAir designation indicates Moldex's electrostatic enhanced media — the same 99.97% NIOSH P100 particle capture at 0.3 microns as any P100, but with lower breathing resistance at equivalent flow rates. That translates to measurably less exhalation effort on extended shifts involving physical labor: welding, grinding, sanding, abrasive blasting, and pharmaceutical manufacturing. P100 particulate filters are change-out-on-schedule items — unlike sorbent cartridges, the P100 filter does not chemically saturate; it is replaced when flow resistance increases perceptibly or when physical integrity is compromised.

The 7740+ is a standalone filter, not a combination cartridge — it provides no gas or vapor protection on its own. For environments with both particulate and gas hazards, either stack the 7740+ on top of a Moldex 7600 Smart cartridge, or use the integrated Moldex 7667 Smart combo. For a full comparison of the Moldex P100 filter lineup including the standard 7740 and the 7760 nuisance OV variant, see our Moldex 7740 vs. 7740+ vs. 7760 filter guide. For the P100-vs-N100 comparison, see our P100 vs. N100 vs. N95 industrial particulate guide. Both the standard Moldex 7740 and the 7740+ IonicAir are available in the Moldex cartridges and filters collection.

Related: Moldex 7760 P100 + nuisance OV/AG filter · P100 vs. N100 vs. N95 guide

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4. Moldex 7667 Smart Multi-Gas + P100 Combo Cartridge — Best combination cartridge

NIOSH class: Multi-Gas + P100 combination · ESLI: Yes · Price: ~$18.50/set · Rating: 4.8/5

The Moldex 7667 Smart is the highest-rated cartridge on this list and the correct selection when your hazard profile requires simultaneous gas/vapor and particulate protection under a single NIOSH approval. It integrates the multi-gas sorbent bed of the Moldex 7600 Smart with a factory-installed P100 particulate filter in a single molded housing — no stacking required, no separate filter purchase, no alignment concerns. The ESLI on the 7667 monitors the gas/vapor sorbent bed; the P100 media is changed on a fixed schedule or when breathing resistance increases. This combination earns the highest user rating of any Moldex cartridge we reviewed (4.8/5) — the combination of ESLI convenience, broad hazard coverage, and the compact single-housing design consistently drives positive field feedback.

The 7667 Smart applies to the widest range of industrial environments: painting and coating operations, welding in enclosed spaces with welding fume and solvent vapor, pharmaceutical manufacturing, and general chemical processing where both gas and aerosol hazards co-exist. For a full discussion of when to use combination cartridges vs. separate stacked filters, see our combination cartridge vs. separate filter guide. Compare to the Moldex 7367 (OV+AG+P100, no ESLI) for programs with a written change-out schedule and narrower hazard scope. Browse the Moldex cartridges collection for in-stock inventory.

Related: Combination cartridge vs. stacked filter — when each applies · Moldex 7467 AM+P100 combo

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5. Moldex 7400 Ammonia/Methylamine Cartridge — Best Moldex cartridge for ammonia

NIOSH class: Ammonia / Methylamine · ESLI: No · Price: ~$33.58/pair · Rating: 4.4/5

The Moldex 7400 is the only dedicated ammonia/methylamine cartridge in the Moldex 7000-series lineup and the correct selection for any operation where ammonia is the primary gas hazard. Ammonia (NH3) and methylamine are not captured by organic vapor sorbent — activated carbon beds in standard OV cartridges have essentially no capacity for ammonia at industrial concentrations. The 7400 uses a specialty sorbent formulation NIOSH-approved for ammonia and methylamine under 42 CFR 84, and it is the legally required cartridge under OSHA 1910.134 for any ammonia-containing environment where air-purifying respirator protection is assigned.

Typical ammonia exposure scenarios requiring the 7400: anhydrous ammonia handling in agricultural and refrigeration applications, ammonia-based cleaning compounds in food processing, wastewater treatment operations, and fertilizer manufacturing. The 7400 does not provide organic vapor or acid gas protection beyond its rated ammonia/methylamine approval — where mixed ammonia and acid gas or OV hazards exist, consult your industrial hygienist. For environments with both ammonia and particulate hazards, see the Moldex 7467 AM+P100 combination cartridge. The higher unit price reflects the specialty sorbent formulation. Change-out must follow a written schedule; no ESLI is available for ammonia cartridges. Browse the full Moldex cartridges collection and pair with a Moldex half-mask respirator.

Related: Moldex 7467 AM/methylamine + P100 combo cartridge · OV vs. OV+AG vs. multi-gas cartridge selection

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6. Moldex 7607 Smart Multi-Gas Cartridge — Best single-unit purchase

NIOSH class: Multi-Gas + ESLI · ESLI: Yes · Price: $6.65/single · Rating: 4.6/5

The Moldex 7607 Smart is the single-unit version of the 7600 Smart — identical protection, identical ESLI, sold individually rather than in pairs. This makes the 7607 the correct purchase for: (1) replacing one cartridge from a pair when the other is still serviceable; (2) programs that issue single cartridges as part of a controlled inventory system; and (3) respirators with a left/right asymmetric cartridge layout where one position sees heavier loading than the other. At $6.65 per unit, the 7607 is essentially the per-unit cost of the paired 7600 — there is no premium for the single-unit packaging, making it a direct price-parity option for programs that need to manage odd-quantity replenishment.

The 7607 carries the same NIOSH approvals as the 7600: organic vapors, acid gases (chlorine, hydrogen chloride, sulfur dioxide, hydrogen sulfide escape-only), and formaldehyde. The ESLI indicator functions identically. It mounts on all Moldex 7000-series half-masks (7001, 7002, 7003) and 9000-series full-face respirators via the standard Moldex bayonet. For full details on the 7000-series mask family, see the Moldex 7000-series half-mask respirator product page and the Moldex half-mask respirator collection.

Related: Moldex 7600 Smart pair · Moldex 7000-series half-mask respirator

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7. Moldex 7367 OV+AG+P100 Combination Cartridge — Best OV+AG+P100 without ESLI

NIOSH class: OV + Acid Gas + P100 combination · ESLI: No · Price: ~$11.62/set · Rating: 4.5/5

The Moldex 7367 is the correct combination cartridge when your program has a documented written change-out schedule, you need organic vapor plus acid gas coverage, and particulate filtration must be integrated in the same housing. It delivers the same three-way hazard coverage (OV + AG + P100) as the 7667 Smart but without the ESLI — making it the lower-cost option for programs where an industrial hygienist has already calculated change-out timing based on exposure modeling or historical sampling. At approximately $11.62 per set, the 7367 offers combination-cartridge protection at a price point close to stand-alone OV cartridges from other manufacturers, making it one of the most cost-efficient full-spectrum combination options on the Moldex platform.

Common applications: spray-paint booths with particulate overspray and solvent vapor, resin and adhesive operations, printing and coating lines with both particulate pigment and solvent carrier vapor. For programs without a written change-out schedule, upgrade to the 7667 Smart — the ESLI provides the compliance pathway the 7367 cannot. For a detailed breakdown of when combination cartridges are the right choice vs. stacked individual cartridges and filters, see our combination cartridge vs. separate filter guide. Browse the full selection at the Moldex cartridges and filters collection.

Related: Combination cartridge vs. separate filter guide · Upgrade to Moldex 7667 Smart (with ESLI)

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Best Moldex cartridge by hazard — selection table

The table below maps common industrial hazard profiles to the correct Moldex 7000-series cartridge. This is a starting reference — actual cartridge selection must be confirmed by reviewing Safety Data Sheets and, where required, an industrial hygienist's written change-out schedule or ESLI verification. For the underlying classification logic, see our OV vs. OV+AG vs. multi-gas cartridge guide.

Which Moldex masks are compatible with these cartridges?

All Moldex 7000-series cartridges and filters use the same proprietary bayonet-style twist-lock mount — one platform, one attachment system. There are no model-specific cartridge exceptions within the 7000-series product family.

Compatible respirators include:

• Moldex 7000-series half-mask respirators — 7001 (Small), 7002 (Medium), 7003 (Large). These are Moldex's standard-volume elastomeric half-masks, the workhorse of the platform. See the Moldex 7000-series half-mask product page and the Moldex half-mask respirator collection.
• Moldex 9000-series full-face respirators — compatible with all 7000-series cartridges and filters, providing APF 50 protection (vs. APF 10 for half-masks). Full-face selection is critical where eye/face splash protection is also required.

Moldex 7000-series cartridges are not cross-compatible with 3M bayonet cartridges, Honeywell North cartridges, or any other manufacturer's cartridge system. A Moldex facepiece requires Moldex cartridges, and a 3M facepiece requires 3M cartridges. This is not a limitation unique to Moldex — all major respirator manufacturers use proprietary attachment systems under NIOSH 42 CFR 84 approval requirements. Browse Moldex cartridges and filters and Moldex half-mask respirators together for correct pairings.

Best Moldex respirator cartridges — frequently asked questions

What is the best Moldex respirator cartridge overall?

For the widest hazard coverage with built-in ESLI, the Moldex 7600 Smart ($20.79/pair, 4.7/5) is the best default selection. It covers organic vapors, acid gases, and formaldehyde, and its ESLI satisfies OSHA 1910.134(d)(3)(iii)(B)(1) without a separate written change-out schedule. For combined gas and particulate protection, the Moldex 7667 Smart is the top-rated option on the platform (4.8/5).

What does ESLI mean on a Moldex Smart cartridge?

ESLI stands for End-of-Service-Life Indicator. Moldex's Smart cartridges incorporate a color-changing chemical indicator strip — typically yellow-green at start of service — that transitions to gray as the activated carbon sorbent bed approaches saturation. Under OSHA 29 CFR 1910.134(d)(3)(iii)(B)(1), a NIOSH-approved ESLI is a recognized alternative to a written change-out schedule. It means the cartridge itself signals when to change, rather than requiring a table-calculated schedule. The ESLI functions at typical ambient temperatures and humidity; extreme humidity or very low concentrations may affect indicator timing. See our full ESLI vs. written change-out schedule guide for the compliance details.

Is the Moldex 7300 better than the 7100?

Yes — the Moldex 7300 is the better purchase at the same price. The 7100 is NIOSH-approved for organic vapors only. The 7300 adds acid gas approval (chlorine, hydrogen chloride, sulfur dioxide, chlorine dioxide) at no price premium. The only reason to specify the 7100 is if your written respiratory protection program explicitly requires OV-only cartridges for a specific reason — and that scenario is uncommon. See our Moldex 7100 vs. 7300 vs. 7600 upgrade guide.

What is the difference between the Moldex 7600 Smart and the Moldex 7667 Smart?

The Moldex 7600 Smart is a gas/vapor cartridge only — no integrated P100 particulate filtration. The Moldex 7667 Smart combines the same multi-gas sorbent bed with a factory-integrated P100 filter in one housing. Both have ESLI. Use the 7600 when your hazard is gas/vapor with no significant particulate loading; use the 7667 (or stack the 7600 with the 7740+ IonicAir) when particulate and gas hazards are both present.

Can I use Moldex cartridges on a 3M respirator?

No. Moldex 7000-series cartridges use a proprietary bayonet mount that is not interchangeable with 3M's bayonet system. Attempting to force-fit cross-brand cartridges is a respiratory protection program violation and may damage the facepiece or create an undetected seal failure. If you use a 3M half-mask or full-face respirator, you need 3M-approved cartridges. If you use Moldex facepieces, you need Moldex cartridges. Browse compatible Moldex facepieces in the Moldex half-mask respirator collection.

What Moldex cartridge do I need for welding?

Welding fume is primarily a particulate hazard (metal fumes, oxides) with potential co-exposure to ozone and nitrogen dioxide at the arc, and solvent vapor if the base metal has surface coatings. For most welding without coated or painted stock, the Moldex 7740+ IonicAir P100 addresses the particulate component. For welding on painted, coated, or galvanized stock where organic vapor and/or acid gas co-exposure is confirmed on the SDS, use the Moldex 7667 Smart (multi-gas + P100, ESLI) or the Moldex 7367 (OV+AG+P100, no ESLI). Confirm cartridge selection with your industrial hygienist based on the SDS of every material present at the welding station.

What Moldex cartridge do I need for spray painting?

Spray painting generates both organic vapor (solvent carrier) and fine aerosol particulate (paint pigment, isocyanate particles in two-part coatings). A combination cartridge is the required selection. The Moldex 7367 (OV+AG+P100, no ESLI, ~$11.62/set) is the cost-efficient option for programs with a written change-out schedule. The Moldex 7667 Smart adds ESLI and broader gas coverage for programs without a calculated schedule. For isocyanate-containing two-part coatings (urethane, epoxy), confirm with your IH that the OV sorbent provides adequate isocyanate protection at your exposure concentrations — this is an IH judgment, not a cartridge-label question.

Do Moldex Smart cartridges work in all lighting conditions?

The Moldex ESLI color-change indicator is most readable in normal ambient or daylight conditions. In very low light — confined spaces, enclosed tanks, poorly lit manufacturing areas — the yellow-green to gray color shift can be difficult to distinguish. OSHA guidance on ESLI performance acknowledges this limitation; programs in low-light environments should supplement ESLI with a documented maximum time limit as a secondary backstop. See our ESLI vs. written change-out schedule guide for the full compliance discussion.

How do I know when to change a Moldex P100 filter?

P100 particulate filters do not chemically saturate the way gas sorbent cartridges do — they load with particulate over time, progressively increasing breathing resistance. Change the Moldex 7740+ IonicAir or any Moldex P100 filter when: (1) breathing resistance increases perceptibly during normal use; (2) the filter is physically damaged, wet, or contaminated; or (3) your program's maximum service-life policy interval is reached. There is no ESLI for P100 filters. For programs with very high particulate loading (heavy abrasive blasting, asbestos abatement), set a fixed time-based change interval. See our Moldex 7740 vs. 7740+ vs. 7760 P100 filter guide.

What is the Moldex 7760 and when do I use it instead of the 7740?

The Moldex 7760 is a P100 particulate filter with a nuisance-level organic vapor and acid gas relief layer added. "Nuisance level" means concentrations below OSHA PEL — not primary gas hazard protection. Use the 7760 only when the particulate is the regulated hazard and low-level solvent odor is a comfort concern, not a compliance concern. If organic vapor or acid gas concentrations meet or exceed OSHA action levels, the 7760 is not a substitute for a cartridge with full OV/AG NIOSH approval. See our Moldex P100 filter comparison guide for the full breakdown.

Is the Moldex 7400 the only option for ammonia on the Moldex platform?

For stand-alone ammonia protection without particulate filtration, yes — the Moldex 7400 is the only dedicated ammonia/methylamine cartridge in the Moldex 7000 lineup. For ammonia plus particulate, the Moldex 7467 AM+P100 combo cartridge combines ammonia/methylamine approval with integrated P100 filtration in a single housing. No Moldex cartridge covers both ammonia and organic vapor in a single housing — if both hazards are present, consult your IH for a program-level solution.

What is the difference between P100 and N100 for industrial particulate?

Both achieve 99.97% filtration efficiency at the most-penetrating particle size (0.3 µm). The difference is oil resistance: N100 is not rated for oil aerosols (no oil resistance); P100 is rated as oil-proof (highest oil resistance classification under 42 CFR 84). For most industrial environments with oil-based aerosols — metalworking fluids, mist coolants, spray lubricants — P100 is the correct selection. N100 is acceptable for environments with no oil aerosol present. See our P100 vs. N100 vs. N95 industrial particulate guide for a full classification breakdown.

Can I use a Moldex 7667 Smart cartridge for asbestos abatement?

Yes — the Moldex 7667 Smart integrates a NIOSH P100 filter, which is the required filter class for asbestos abatement air-purifying respirators under OSHA 29 CFR 1926.1101. The combination with multi-gas sorbent is appropriate where solvent or gas co-exposure is also present. For pure asbestos particulate (no gas co-exposure), the stand-alone Moldex 7740+ IonicAir P100 stacked on a gas cartridge or used alone is equally protective for the particulate hazard. Always confirm the facepiece has passed a NIOSH-protocol fit test before use in asbestos abatement.

Which Moldex cartridges require a written change-out schedule?

All Moldex cartridges without ESLI require a documented written change-out schedule under OSHA 29 CFR 1910.134(d)(3)(iii)(B)(2). That includes the Moldex 7300, 7400, 7367, and all non-Smart cartridges. Cartridges with ESLI — the 7600 Smart, 7607 Smart, and 7667 Smart — satisfy the OSHA change-out requirement through the ESLI indicator under clause (B)(1). P100 particulate filters (7740, 7740+, 7760) are not subject to the sorbent change-out schedule — they are changed based on breathing resistance and physical condition, with a program-defined maximum interval. See our ESLI vs. written change-out schedule guide for details.

What is the best Moldex cartridge for construction and general industry?

For construction and general industry environments with mixed or uncertain vapor hazards, the Moldex 7600 Smart is the practical default — broadest gas coverage, ESLI, and no written schedule required. Where particulate is also present (common in construction: silica dust, lead dust, welding fume), step up to the Moldex 7667 Smart for integrated gas+P100 protection. Pair either cartridge with a Moldex 7000-series half-mask in the correct size, fit-tested per OSHA 1910.134 Appendix A before first use.

How do Moldex Smart cartridges compare to 3M cartridges with OV/P100 ratings?

The core difference is the ESLI: Moldex's Smart cartridges have a factory-integrated ESLI; most 3M cartridges in the equivalent class rely on written change-out schedules or a separately purchased ESLI accessory. NIOSH approval standards are identical across manufacturers — a Moldex P100 captures the same 99.97% of 0.3 µm particles as a 3M P100. The practical decision between Moldex and 3M cartridges turns on (1) which facepiece your program has already standardized on — cartridges are not cross-compatible — (2) ESLI availability for your hazard class, and (3) price and availability at volume. For platform selection and in-stock Moldex inventory, see the Moldex cartridges collection.

Does Moldex make cartridges for their 9000-series full-face respirators?

Yes — all Moldex 7000-series cartridges and filters are compatible with Moldex 9000-series full-face respirators using the same bayonet-style mount. There is no separate full-face-specific cartridge line; the same 7600 Smart, 7667 Smart, 7740+, 7300, and 7400 that mount on the 7000-series half-masks also mount on the 9000-series full-face units. The 9000-series provides APF 50 (vs. APF 10 for the 7000-series half-masks) and adds integrated eye and face protection. Browse the full Moldex cartridges and filters collection for in-stock inventory across both platforms.

What is the Moldex 7667 Smart rated at and what hazards does it cover?

The Moldex 7667 Smart is NIOSH-approved for organic vapors, chlorine, hydrogen chloride, sulfur dioxide, hydrogen sulfide (escape), formaldehyde, and P100 particulates — in a single combination housing with ESLI monitoring the gas sorbent bed. It is the single broadest-coverage combination cartridge in the Moldex 7000-series lineup and carries the platform's highest user rating at 4.8/5.