Is the Moldex 7667 the ultimate Moldex cartridge for full chemical-plus-particulate protection?

Moldex 7667 Multi-Gas P100 Combo Smart Cartridge Review (2026)

Combination cartridges — assemblies that handle both gas/vapor and particulate hazards in one unit — represent the most demanding tier of respiratory protection. They are selected when the hazard profile includes both chemical vapors and aerosols simultaneously: spray painting with solvent-based coatings, pesticide application, chemical processing environments where acid gas and dust coexist, and pharmaceutical coating lines are the classic examples. Within the Moldex cartridge lineup, three combination assemblies exist, but only one delivers Moldex's broadest gas coverage, P100 particulate efficiency, and a factory-installed ESLI in the same package: the Moldex 7667.

The 7667 is designated a "Smart" assembly because it incorporates the same color-change ESLI technology found in Moldex's 7600 series standalone Smart cartridges. The ESLI indicator window turns from yellow to dark blue as the activated carbon bed reaches service-life saturation — providing a passive, visual end-of-service-life signal without requiring separate air sampling. That feature places the 7667 in OSHA 29 CFR 1910.134(d)(3)(iii)(B)(2) compliance territory for employers seeking an objective change schedule indicator rather than a purely time-based protocol.

Each 7667 set sold contains one multi-gas Smart cartridge body (7607 chemistry) and one P100 particulate filter (7740). Because respirators use two cartridges, a complete respirator setup requires two sets, bringing the total investment to approximately $37.00 per respirator load. That is the premium pricing tier among Moldex combination cartridges — a trade-off evaluated in detail in the cost-of-ownership section below.

This review covers the 7667's protection profile, ESLI function, compatible respirator platforms, comparisons against competing assemblies, and practical guidance on when the 7667 is — and is not — the right selection. All analysis is based on NIOSH certification data, Moldex published specifications, and OSHA regulatory requirements; no independent laboratory testing was conducted.

Who Should Buy the Moldex 7667

The 7667 is the correct selection when all of the following are true:

• You already use a Moldex respirator platform — either a Moldex 7000-series half-mask or a Moldex 9000-series full-face respirator.
• Your hazard profile includes both gas/vapor and particulate simultaneously — typical examples: spray painting with solvent-based coatings over surfaces with acid-gas co-exposure, pesticide spraying (liquid aerosol + OV), pharmaceutical tablet coating (dust + solvent vapor), chemical processing lines.
• Your application requires an ESLI — either because OSHA requires an objective change schedule indicator for the specific chemical exposure, or because your written respiratory protection program (WRPP) calls for one, or because your industrial hygienist has recommended it over a purely time-based schedule.
• Ammonia and methylamine are not primary hazards — if they are, the Moldex 7467 is the correct combination choice.

The 7667 is less appropriate for workers who only need particulate protection (use the standalone Moldex 7740 P100 filter), or only gas/vapor protection without particulate (use the standalone Moldex 7607 Smart cartridge). Purchasing the combination assembly when only one hazard type is present means paying for unused filtration capacity.

What the Moldex 7667 Does Well

1. The Only Moldex P100 Combination Cartridge with a Built-In ESLI

This is the defining feature of the 7667 and the primary reason it commands a premium price. Across the full Moldex combination cartridge range — the 7367 OV+AG+P100, the 7467 Ammonia+P100, and the 7667 Multi-Gas+P100 Smart — only the 7667 includes an ESLI.

The ESLI uses a proprietary Moldex indicator strip embedded in the cartridge body. As organic vapors and acid gas contaminants saturate the activated carbon, the indicator window changes color from yellow to dark blue. Under OSHA 29 CFR 1910.134(d)(3)(iii)(B)(2), a cartridge fitted with an ESLI that has been approved by NIOSH for the specific contaminant present satisfies the requirement to determine cartridge change frequency without mandating a separate air-concentration-based calculation. This is significant for employers whose written respiratory protection programs need a defensible, documented change-out mechanism. Read more about change schedule requirements in our reference guide on respirator cartridge service life.

For workers in field environments — pesticide application, spray operations — where real-time air sampling is impractical, the ESLI provides a passive, continuous indication that requires no equipment, calibration, or calculation. That is a genuine operational advantage that no other Moldex P100 combination assembly can provide.

2. Broad Multi-Gas and Vapor Coverage

The 7667's gas-cartridge chemistry — the same 7607 formulation used in Moldex's standalone Smart cartridge — provides protection against a wider range of chemical classes than any other Moldex combination assembly:

• Organic vapors (solvents, petroleum distillates, paint thinners)
• Acid gases: hydrogen chloride (HCl), chlorine (Cl₂), hydrogen fluoride (HF), sulfur dioxide (SO₂), hydrogen sulfide (H₂S)
• Formaldehyde
• Chlorine dioxide (ClO₂)

Formaldehyde protection is particularly relevant in embalming, healthcare, and certain manufacturing processes. Chlorine dioxide coverage matters in water treatment and food processing applications. Neither of these is included in the 7367's acid-gas cartridge or in 3M's 60926 cartridge at equivalent concentrations. For buyers researching cartridge selection by chemical class, our respirator cartridge color chart and cartridge selection guide provide a broader comparison.

3. P100 Particulate Filtration at ≥99.97% Efficiency

The P100-rated Moldex 7740 filter component of the 7667 assembly is tested and approved by NIOSH under 42 CFR 84 at ≥99.97% filtration efficiency against 0.3-micron particles — the most penetrating particle size. The "P" designation confirms the filter is rated for use against oil-based aerosols as well as dry particulate, which is necessary in many spray and chemical-process environments where both oil-mist and solid particulate may be present.

The P100 efficiency level is the highest available under the NIOSH particulate classification system, surpassing N100 (oil-not-tested), R100 (limited oil resistance), and the P95/N95 grades. For combined chemical-plus-particulate environments, P100 provides the broadest and most reliable aerosol protection available in an air-purifying respirator.

4. Formaldehyde and Chlorine Dioxide Coverage Beyond Standard OV+AG

The distinction between "OV+AG" cartridges (like the 7367) and "Multi-Gas" Smart cartridges (like the 7667) is not merely marketing. The 7667's activated carbon formulation includes specific sorbent chemistry targeting formaldehyde, which is a small, polar molecule that standard organic-vapor carbon beds can pass through at higher concentrations. Workers in healthcare environments handling tissue fixatives, in composite manufacturing with formaldehyde-releasing resins, or in wood products manufacturing where formaldehyde off-gassing is present require this specific coverage. No other Moldex P100 combination cartridge provides it. See our guides on best cartridges for acid gas and best cartridges for solvents for context on how the 7667 fits into broader hazard-specific selections.

Where the Moldex 7667 Falls Short

1. No Ammonia or Methylamine Protection

Ammonia (NH₃) and methylamine are not captured by the 7667's activated carbon formulation. These are alkaline gases that require a different sorbent chemistry than the acid-gas-and-OV media in the 7667. Workers in refrigeration maintenance, water treatment (ammonia feed), poultry processing, fertilizer operations, and some chemical manufacturing environments where ammonia is a primary vapor hazard need the Moldex 7467 Ammonia+P100 combination cartridge instead. Do not attempt to use the 7667 as ammonia protection — it will not provide it, and no color change on the ESLI will indicate ammonia breakthrough.

2. Highest Per-Setup Cost in the Moldex Combination Line

At approximately $18.50 per bag (one set = one cartridge + one P100 filter), and requiring two sets per respirator, a complete 7667 respirator load costs approximately $37.00. By comparison, the 7367 OV+AG+P100 is cheaper per setup. The price premium for the 7667 is the ESLI and the broader gas coverage. For applications where OSHA permits a standard time-based change schedule and neither formaldehyde nor chlorine dioxide is present, the 7367 may deliver adequate protection at lower cost. The total cost of ownership analysis in a later section addresses how the ESLI may partially offset this premium.

3. Ammonia Applications Require the 7467 Instead

Worth stating directly: there is no single Moldex combination cartridge that provides both ammonia/methylamine coverage and ESLI. The 7467 provides ammonia+methylamine+P100 but has no ESLI. If ammonia is a known co-hazard alongside organic vapors and particulate, a qualified industrial hygienist should assess whether the 7667 (which covers the OV+acid gas side) combined with ammonia monitoring or a separate ammonia-specific schedule is appropriate, or whether a different respirator system entirely is indicated. The Moldex combination cartridge lineup does not currently offer a single assembly combining ammonia, multi-gas, and ESLI in one unit.

4. Moldex-Proprietary Mount Limits Platform Flexibility

The 7667 uses Moldex's bayonet-style proprietary mount. It is not compatible with 3M, Honeywell, MSA, or any other manufacturer's respirator facepieces. Organizations standardized on multi-brand respirator programs, or workers who use 3M facepieces as their primary platform, will need to evaluate 3M's 60926 or 60921 combination cartridges. The 3M 60926 is reviewed in the comparison table below.

Comparison: Moldex 7667 vs 3M 60926 vs 3M 60921

How does the 7667 stack up against the most commonly specified 3M P100 combination cartridges? The critical differentiator is ESLI: as of this review's publication date, neither the 3M 60926 nor the 3M 60921 includes a factory-installed ESLI. 3M offers ESLI technology on certain standalone OV cartridges (the 3M 6001i series) but not on their P100 combination assemblies.

Key takeaway: If you are already on the Moldex platform and need an ESLI on your combination cartridge, the 7667 is currently the only option available from any major manufacturer in the P100 combination category that includes a factory-installed ESLI. 3M's combination cartridges require buyers to rely on time-based change schedules or separate ESLI products; neither the 60926 nor the 60921 provides one in the combination format.

Choosing Within the Moldex Combination Cartridge Line

Moldex offers three combination assemblies. The table below isolates the differentiators to simplify selection. The ESLI row is highlighted because it is the primary feature distinguishing the 7667 from the rest of the Moldex combination range.

Decision rules — use this list to choose between Moldex combination cartridges:

• If your primary gas hazards are organic vapors and acid gases, no ESLI is required by your program, and formaldehyde is not present — choose the Moldex 7367.
• If your primary gas hazard is ammonia or methylamine alongside particulate — choose the Moldex 7467.
• If your hazard profile includes OV + acid gases + formaldehyde or chlorine dioxide, and/or your written respiratory protection program requires an ESLI — choose the Moldex 7667.
• If ammonia and multi-gas coverage are both required simultaneously — consult a qualified industrial hygienist; no single Moldex combination cartridge covers both.

Compatible Moldex Respirators

The Moldex 7667 uses Moldex's proprietary bayonet mount — the same fitting used across the entire Moldex 7000- and 9000-series respirator platforms. Installation is tool-free: align the bayonet tabs, press, and rotate to lock. The assembly mounts identically on all compatible facepieces.

Compatible Moldex respirator series:

• Moldex 7000-series half-mask respirators — 7001 (S), 7002 (M), 7003 (L). Assigned Protection Factor (APF): 10. Suitable for contaminant concentrations up to 10x the applicable exposure limit when cartridge is properly selected. Browse the full Moldex half-mask respirator collection.
• Moldex 7800-series half-mask respirators — uses the same bayonet fitting. APF: 10.
• Moldex 9000-series full-face respirators — 9001 (S), 9002 (M/L), 9003 (L/XL). APF: 50. Suitable for contaminant concentrations up to 50x the applicable exposure limit when properly selected and fit-tested. Browse the Moldex full-face respirator collection.

APF selection note: If the air concentration of a contaminant exceeds 10x the PEL/TLV, a half-mask with APF 10 is insufficient. Step up to the Moldex 9000 full-face with APF 50. If concentrations exceed 50x the exposure limit, air-purifying respirators are generally not appropriate and supplied-air or SCBA should be evaluated.

Category Context: Combination Cartridge Design and Why ESLI Matters More in P100 Combos

Combination cartridges integrate two filtration mechanisms in one assembly: a gas-phase sorbent (activated carbon, typically impregnated with additional chemistry for specific gas classes) and a mechanical particulate filter membrane. The particulate filter is physically positioned to capture aerosols before they reach the gas sorbent, which also protects the carbon bed from loading with liquid droplets that would reduce its gas-phase capacity.

In a standalone gas-only cartridge, the ESLI provides direct indication of the gas-phase sorbent's remaining capacity. In a combination assembly, the P100 filter is a discrete physical component with its own change schedule based on breathing resistance, physical damage, or contamination — not on the ESLI. The ESLI on the 7667 indicates the gas-cartridge component's chemical saturation; the P100 filter is changed separately per the manufacturer's P100 change guidelines.

Why does ESLI matter more in P100 combination cartridges than in standalone gas cartridges? Because combination cartridge users are typically in more hazardous, mixed-exposure environments. A worker using a simple OV cartridge for low-concentration solvent work in a ventilated shop has a lower-risk profile than a worker in a spray booth applying chemical coatings with concurrent acid-gas and aerosol exposure. The more severe the exposure scenario, the more consequential it is to misjudge cartridge change timing. In those environments, the ESLI shifts the change decision from an estimate to an observed indicator, reducing the risk of working past the cartridge's chemical protection capacity.

For a deeper look at how combination cartridge selection fits into a complete respiratory protection program, see our guides on respirator cartridge selection for epoxy and chemical spray and browse the full respirator filters and cartridges collection.

Total Cost of Ownership

The 7667 is the highest-priced Moldex combination cartridge assembly. Understanding the full cost picture requires factoring in the ESLI's potential to extend useful cartridge life beyond a conservative fixed-schedule approach.

Per-use cost breakdown:

• One 7667 set (1 gas cartridge + 1 P100 filter): approximately $18.50
• Two sets required per respirator (one for each side): approximately $37.00 per complete respirator load
• The P100 filter (7740 component) is typically rated for extended use until breathing resistance increases noticeably or the filter is physically damaged — it is not the cost-driver in most change cycles
• The gas cartridge is the primary consumable; change frequency drives ongoing cost

How the ESLI affects total cost:

Under a purely time-based change schedule (e.g., change every shift, or every 8 hours), the gas cartridge is replaced on a fixed cadence regardless of remaining capacity. In lower-exposure environments — applications where contaminant concentrations are well below the PEL — a cartridge changed on a conservative schedule may have significant remaining capacity when discarded.

The ESLI enables capacity-based change scheduling: the cartridge is changed when the indicator shows saturation rather than on a fixed time interval. In practice, this can extend cartridge life in lower-concentration environments, partially offsetting the 7667's higher unit price relative to the 7367. The precise cost impact depends on the specific exposure concentrations, humidity, temperature, and usage pattern — all of which affect ESLI response rate. Buyers should not assume the ESLI will always extend service life; in high-concentration or high-humidity environments the indicator can change rapidly.

For ongoing supply, the standalone components are also available separately: the Moldex 7607 Smart gas cartridge and the Moldex 7740 P100 filter can be purchased individually if one component reaches end of life before the other, avoiding the need to replace the full assembly simultaneously.

Final Verdict

The Moldex 7667 Multi-Gas P100 Combo Smart Cartridge earns its 4.8/5 rating and its position as the flagship combination cartridge in the Moldex lineup. The combination of multi-gas coverage (including formaldehyde and chlorine dioxide beyond standard OV+AG), P100 particulate efficiency, and the only factory-installed ESLI in any Moldex P100 combination assembly makes it the unambiguous choice for Moldex-platform users who need both objective end-of-service-life indication and broad chemical protection in a single assembly.

It is not the right choice for every buyer. If ammonia is a primary hazard, the 7467 is required. If the hazard profile is simpler OV+AG without formaldehyde and without an ESLI requirement, the 7367 delivers adequate protection at lower cost. But for the buyer whose situation calls for everything the 7667 delivers — especially the ESLI in a P100 combination format — there is currently no competing Moldex assembly, and no broadly available alternative from other manufacturers, that matches the feature set.

Browse the complete Moldex cartridge and filter collection or view the 7667 directly on WC Safety.

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Frequently Asked Questions — Moldex 7667 Multi-Gas P100 Combo Smart Cartridge