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MSA GMC Respirator Cartridge — Organic Vapor And Acid Gas (MSA Comfo)

MSA Safety SKU: 464046 Respirator Cartridge GTIN: 0641817007549
★ ★ ★ ★ ★ 5.0 (2 Amazon customer ratings)
$103.45
Final price set by Amazon · may vary

EDITORIAL REVIEW: 4.6/5WC Safety Review — MSA GMC Respirator Cartridge Best For: organic vapor and acid gas exposure with little or no dust on MSA Comfo respirators. Not For: dust, mist or ammonia or particulate. ...

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Acid Gas APR Combination Cartridge Comfo Respirator MSA Safety NIOSH Approved Organic Vapor Respirator Cartridge
EDITORIAL REVIEW: 4.6/5WC Safety Review — MSA GMC Respirator Cartridge

Best For: organic vapor and acid gas exposure with little or no dust on MSA Comfo respirators.

Not For: dust, mist or ammonia or particulate. It is a gas cartridge only.

Bottom Line: the gas-only organic vapor and acid gas choice for the MSA Comfo system. Add dust protection with the GMC/P100 when particulate is present.

Editorial assessment by Steven Eaton, WC Safety editor. Scoring reflects published MSA specifications, NIOSH approval, application fit and category expertise. WC Safety did not laboratory-test this product.

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Read our MSA GMC review for the detailed review.

MSA GMC Respirator Cartridge Overview

The MSA GMC is a NIOSH-approved organic vapor and acid gas cartridge for the MSA Comfo system. It adsorbs solvent vapors plus chlorine, hydrogen chloride and sulfur dioxide and carries a yellow (ov/acid gas) band. As a Comfo cartridge it fits MSA Comfo Classic, Comfo II, Ultra-Twin and Ultra-Elite respirators. Start with our guide to choosing a respirator cartridge, confirm the band on the respirator cartridge color chart, and see MSA Comfo vs Advantage if you are unsure which system you own.

The MSA GMC belongs to the MSA respirator filters and cartridges range. It is a gas cartridge only — for dust, step up to the GMC/P100 combination cartridge, which builds a P100 filter in.

Where the MSA GMC Fits in Cartridge Selection

Confirm the hazard before the cartridge. The MSA GMC handles organic vapor and acid gas gas — not particulate. If you also face dust or mist, our organic vapor vs P100 guide and filter types explained cover when to move to a combination cartridge.

Who Should Buy the MSA GMC?

Buy it if your exposure is organic vapor and acid gas with no significant dust, on an MSA Comfo facepiece. Choose another cartridge if your hazard differs: for organic vapor and acid gas plus dust use the GMC/P100, and for a broader gas mix see the MSA Comfo GME multi-gas cartridge.

What Does the MSA GMC Protect Against?

Hazard Fit Buyer guidance
Organic Vapor And Acid Gas (solvent vapors plus chlorine, hydrogen chloride and sulfur dioxide) Yes The sorbent bed.
Dust, mist, fume (particulate) No Add a prefilter or use the GMC/P100 (P100) version.
Ammonia Or Particulate No Use the matching MSA cartridge for that hazard.

What the MSA GMC Does NOT Protect Against

The MSA GMC does not capture particulate or ammonia or particulate. For dust, step up to the GMC/P100 combination cartridge, which builds a P100 filter in; for a different gas, match the MSA cartridge to the hazard.

No air-purifying cartridge makes a dangerous atmosphere safe. Never use the MSA GMC in an oxygen-deficient or IDLH (immediately dangerous to life or health) atmosphere, in unknown concentrations, or against gases with no warning properties — those conditions require a supplied-air or SCBA system, not a cartridge respirator. A cartridge or filter carries no assigned protection factor of its own — the APF comes from the facepiece it is fitted to: 10 for a half mask, 50 for a full facepiece (OSHA 1910.134 Table 1), which is the number that decides the highest exposure the respirator may legally be worn in. That facepiece must be fit tested before first use and at least annually, and a fit test is specific to one make, model, and size — passing on one mask does not carry over to another. Perform a user seal check every time the respirator is donned, and note that facial hair crossing the sealing surface disqualifies a tight-fitting respirator no matter how well it fit at the last test.

Best Applications

Chemical handling

Tasks mixing solvents and acid gases; see GMC/P100 vs 3M 60923.

Lab & treatment

Where both vapor classes appear; add a prefilter for dust or use the GMC/P100.

Pros & Cons

Pros
NIOSH-approved organic vapor and acid gas protection · genuine MSA Comfo fit · yellow (ov/acid gas) band for quick ID · lighter and cheaper than a combination cartridge
Cons
gas only — no particulate protection · Comfo connection only (not cross-compatible) · one gas class

MSA GMC vs Other MSA Cartridges

Cartridge Protects against
MSA GMA Organic vapor
MSA GMB Acid gas
MSA GME Multi-gas
MSA GMC/P100 OV/AG + P100

MSA GMC vs the Alternatives

How it compares to the closest MSA options:

  • GMC vs GMC/P100: same dual-gas protection; the GMC/P100 adds a P100 filter.
  • GMC vs GME: the GME multi-gas adds ammonia and formaldehyde to the mix.
  • GMC (Comfo) vs Advantage GMC: same chemistry, different facepiece system.

MSA GMC Quick Answers

Does the MSA GMC filter dust?

No — it is gas-only; for particulate use the GMC/P100 or add a prefilter.

Does the MSA GMC fit my MSA respirator?

It fits the MSA Comfo family. Check your facepiece against the MSA half-mask and full-face ranges.

Is the MSA GMC reusable?

The cartridge is used until its service life is reached; the respirator is reusable across many cartridge changes.

MSA GMC Specifications

Gas class Organic Vapor And Acid Gas
Particulate None (gas cartridge)
NIOSH band Yellow (OV/acid gas) band
Connection MSA Comfo
Sold as Each

Compatible MSA Respirators

The MSA GMC uses the MSA Comfo threaded-bayonet connection, so it mounts on the Comfo Classic half-mask and Ultra-Elite full-face respirators (and the Comfo II and Ultra-Twin). It is not interchangeable with the MSA Advantage series, and does not fit 3M, Honeywell North or other brands.

Respirator Type Compatible?
MSA Comfo Classic Half mask Yes — Comfo bayonet
MSA Comfo II Half mask Yes — Comfo bayonet
MSA Ultra-Elite Full face Yes — Comfo bayonet
MSA Ultra-Twin Full face Yes — Comfo bayonet
MSA Advantage series Half / full No — different connection
3M / Honeywell North Half / full No (not compatible)

Helpful Buying Guides

MSA GMC Frequently Asked Questions

What does the MSA GMC protect against?

The MSA GMC is a organic vapor and acid gas cartridge. It adsorbs solvent vapors plus chlorine, hydrogen chloride and sulfur dioxide. It is gas-only and does not filter particulate; it does not protect against ammonia or particulate.

Does the MSA GMC filter dust?

No. It is a gas cartridge. For dust or mist, step up to the GMC/P100 combination cartridge, which builds a P100 filter in.

Which respirators does the MSA GMC fit?

It uses the MSA Comfo threaded-bayonet connection and fits the Comfo Classic, Comfo II, Ultra-Twin and Ultra-Elite. It does not fit the Advantage series.

What color band is the MSA GMC?

The MSA GMC carries a yellow (ov/acid gas) band; confirm it on the cartridge color chart before use.

Is the MSA GMC NIOSH-approved?

Yes. The MSA GMC is NIOSH-approved under 42 CFR Part 84 for organic vapor and acid gas. Verify any cartridge against the NIOSH Certified Equipment List.

How is the MSA GMC sold?

This listing is the Each. Case pricing comes from an industrial distributor; we do not quote.

How often should I replace the MSA GMC?

Replace the cartridge on a documented change-out schedule based on objective data, or when an end-of-service-life indicator shows it is spent, and whenever it is damaged. Under 29 CFR 1910.134(d)(3)(iii)(B) the change schedule must rest on objective data or an end-of-service-life indicator — odour, taste or irritation may not be the primary basis. If you can smell or taste anything through the cartridge, breakthrough has already happened: leave the area immediately and change it..

Can I add a P100 filter to the MSA GMC?

Yes — the easiest route is the GMC/P100, which builds a P100 particulate filter into the same gas cartridge.

Is the MSA GMC the same as the Advantage version?

No. The chemistry is equivalent, but the connection differs — Comfo and Advantage cartridges are not interchangeable. Match the cartridge to your facepiece.

Is this the genuine MSA GMC cartridge?

Yes. Buy authentic, NIOSH-approved MSA GMC cartridges through legitimate channels only.

What is the difference between the MSA GMC and a multi-gas cartridge?

A single-class cartridge is tuned to its listed gases; a multi-gas cartridge covers a broader mix at the cost of a shorter service life against any one gas.

How should I store the MSA GMC?

Store it sealed in its original packaging, away from gases and dust, so the sorbent is not used up before you wear it.

Written by Steven Eaton, WC Safety Editorial — industrial respiratory protection desk. Reviewed by Steven Eaton, WC Safety editor. Specifications sourced from MSA Safety published data and verified against the NIOSH Certified Equipment List. Compare the range in MSA respirator filters & cartridges or read MSA Comfo vs Advantage.

WC Safety is an independent PPE review site and Amazon Associate; no paid placement. Always verify cartridge compatibility and follow your written respiratory protection program. General information, not medical or regulatory advice.

Read our detailed MSA GMC Respirator Cartridge review — strengths, limitations, and the alternatives that matter.

Brand / Vendor
MSA Safety
Model / SKU
464046
Product Type
Respirator Cartridge
Price
$103.45 (Amazon)
Rating
5.0 / 5 — 2 Amazon ratings
Availability
Check current availability on Amazon
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Independent Product Research
Product information is compiled from manufacturer specifications, published standards information, compatibility data, and other cited sources.
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Verified Buyer Reviews

Customer Reviews

★★★★★5.0 / 5· 2 ratings on Amazon
★★★★★
Protects against harmful organic vapors
These cartridges work great against organic vapors & zinc oxide.
Verified Purchaser · September · ✓ Amazon Verified Purchase
Showing 1 of 2 Amazon reviews.
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MSA GMC Respirator Cartridge — Organic Vapor And Acid Gas (MSA Comfo)