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Industrial Safety Equipment & PPE — ANSI/OSHA Compliant
Industrial Safety Equipment & PPE — ANSI/OSHA Compliant

Honeywell North Cartridge Guide: Complete Selection Hub for Filters & Respirator Cartridges

The Honeywell North cartridge guide and selection hub. Every Honeywell North respirator cartridge shares one universal North bayonet, so the entire 7700, 5500, 7600, and 5400 lineup runs on a single platform. This Honeywell North cartridge chart helps you choose the correct cartridge by contaminant, by job, by respirator cartridge compatibility, and by exact model — with a direct product page and SKU review link for every cartridge and filter.

Start Here: Which Honeywell North Cartridge Do You Need?

Choose by hazard first, then by whether you need P100 particulate protection.

How This Honeywell North Cartridge Guide Was Built

This Honeywell North cartridge guide is organized around the principles that determine whether a respirator actually protects the wearer:

  • Cartridge selection depends on the contaminant — the facepiece holds the seal; the cartridge must match the specific hazard.
  • P100 filters protect against particulates, not gases or vapors by themselves.
  • Gas and vapor cartridges are selected by contaminant class — organic vapor, acid gas, ammonia/methylamine, or multi-gas.
  • North cartridges must match compatible Honeywell North respirators (5500, 7700, 5400, 7600) via the proprietary North bayonet.
  • Occupational respirator use requires a hazard assessment, fit testing, and a change-out schedule under OSHA 29 CFR 1910.134.
  • This guide is for product-selection education and does not replace OSHA requirements, SDS review, or a formal respiratory protection program.

For method, see How to Choose a Respirator Cartridge, the Respirator Cartridge Color Chart, P100 vs N95, and OSHA 29 CFR 1910.134.

What Honeywell North Cartridge Do I Need?

Answer: Match the cartridge to the contaminant. Particulate uses a North P100 (7580P100 / 75FFP100); organic vapor uses the N75001L or 7581P100L; acid gas and formaldehyde use the N75002L or 7582P100L; ammonia uses the N75004L or 7584P100L; and mixed or uncharacterized exposures use the 75SCP100L multi-contaminant cartridge. P100 included: yes. Product: Honeywell North 75SCP100L Multi-Contaminant/P100 Cartridge; review: 75SCP100L Review. See the cartridge selection guide.

Honeywell North Cartridge Quick Selection Chart

Match your exposure to a Honeywell North cartridge. The Recommended Cartridge links to the product page; the Full Review links to the SKU review.

Exposure / Job Type Recommended Cartridge P100 Included? Best For Full Review
Silica, lead, mold, welding fume (particulate) Honeywell North 7580P100 P100 Filter Yes (standalone) Particulates only — silica, lead, asbestos, welding fume, and mold spores at 99.97% 7580P100 Review
Dust, fume, spores (low-profile P100) Honeywell North 75FFP100 P100 Filter Yes (standalone) Particulates only — dust, mist, fume, and spores at 99.97%, in a low-profile disc 75FFP100 Review
Paint fumes, solvents, organic vapor Honeywell North N75001L Organic Vapor Cartridge No Organic vapors — solvents, fuels, paint vapor, adhesives N75001L Review
Spray painting, solvent + dust Honeywell North 7581P100L Organic Vapor / P100 Cartridge Yes Organic vapors plus particulate — solvents and overspray mist together 7581P100L Review
Chlorine, acid gas (vapor only) Honeywell North N75002L Acid Gas Cartridge No Acid gases — chlorine, hydrogen chloride, sulfur dioxide, hydrogen fluoride N75002L Review
Acid gas + formaldehyde + mist Honeywell North 7582P100L Acid Gas / Formaldehyde / P100 Cartridge Yes Acid gases (chlorine, HCl, SOâ‚‚), formaldehyde, plus P100 particulate 7582P100L Review
Mixed organic vapor + acid gas Honeywell North N75003L Organic Vapor / Acid Gas Cartridge No Organic vapor and acid gas together, no particulate N75003L Review
2K paint, coated-metal welding Honeywell North 7583P100L Organic Vapor / Acid Gas / P100 Cartridge Yes Organic vapor, acid gas, and P100 particulate 7583P100L Review
Ammonia / methylamine Honeywell North N75004L Ammonia/Methylamine Cartridge No Ammonia and methylamine, no particulate N75004L Review
Ammonia + dust/mist Honeywell North 7584P100L Ammonia/Methylamine/P100 Cartridge Yes Ammonia, methylamine, plus P100 particulate 7584P100L Review
Multi-gas + particulate (maintenance) Honeywell North 75SCP100L Multi-Contaminant/P100 Cartridge Yes Organic vapor, acid gas, ammonia, methylamine, formaldehyde, plus P100 75SCP100L Review
Multi-gas vapor (no particulate) Honeywell North 75SCL Defender Multi-Gas Cartridge No Broad gas/vapor — organic vapor, acid gas, ammonia, methylamine, formaldehyde 75SCL Review
Light non-oil dust over a cartridge Honeywell North 7506N95 Prefilter Prefilter Light non-oil particulate over a vapor cartridge 7506N95 Review
Higher-efficiency non-oil dust Honeywell North 7506N99 Prefilter Prefilter Higher-efficiency non-oil particulate over a vapor cartridge 7506N99 Review
Oil-resistant dust/mist over a cartridge Honeywell North 7506R95 Prefilter Prefilter Oil-resistant particulate over a vapor cartridge (≤8 hr) 7506R95 Review
Economy R95 oil-resistant prefilter Honeywell North 7504R95 Prefilter (2-Pack) Prefilter Economical oil-resistant particulate pads over a vapor cartridge 7504R95 Review

Honeywell North Respirator Cartridge Compatibility

All North bayonet cartridges and filters fit all four North reusable facepiece families. North cartridges must be used with compatible Honeywell North respirators — do not use Honeywell North cartridges on 3M respirators, and do not use 3M cartridges on Honeywell North respirators.

Cartridge / Filter North 5500 North 7700 North 5400 North 7600 Notes
7580P100 Yes Yes Yes Yes P100 particulate filter
75FFP100 Yes Yes Yes Yes P100 particulate filter
N75001L Yes Yes Yes Yes Organic vapor cartridge
7581P100L Yes Yes Yes Yes Organic vapor + P100 combination
N75002L Yes Yes Yes Yes Acid gas cartridge
7582P100L Yes Yes Yes Yes Acid gas + formaldehyde + P100 combination
N75003L Yes Yes Yes Yes Organic vapor + acid gas cartridge
7583P100L Yes Yes Yes Yes Organic vapor + acid gas + P100 combination
N75004L Yes Yes Yes Yes Ammonia / methylamine cartridge
7584P100L Yes Yes Yes Yes Ammonia / methylamine + P100 combination
75SCP100L Yes Yes Yes Yes Multi-contaminant (OV/AG/ammonia/methylamine/formaldehyde) + P100
75SCL Yes Yes Yes Yes Defender multi-purpose multi-gas cartridge (NO integrated P100)
7506N95 Yes Yes Yes Yes N95 prefilter (disc)
7506N99 Yes Yes Yes Yes N99 prefilter (disc)
7506R95 Yes Yes Yes Yes R95 prefilter (oil-resistant)
7504R95 Yes Yes Yes Yes R95 prefilter (2-pack)

Half masks (5500, 7700) give an APF of 10; full face (5400, 7600) give an APF of 50 and protect the eyes. Compare them in the 5500 vs 7700 and 5400 vs 7600 comparisons.

Honeywell North Cartridge Chart by Contaminant

Contaminant Class North Cartridge (no P100) North Cartridge (with P100) Not For
Organic vapor N75001L 7581P100L Acid gas, ammonia, particulate-only
Acid gas / formaldehyde N75002L 7582P100L Organic vapor, ammonia
Organic vapor + acid gas N75003L 7583P100L Ammonia
Ammonia / methylamine N75004L 7584P100L Acid gas, organic vapor
Multi-gas / uncharacterized 75SCL 75SCP100L Above-IDLH or confined space
Particulate (silica, lead, fume, spores) — 7580P100 / 75FFP100 Any gas or vapor

Honeywell North P100 Filter vs Chemical Cartridge

The most common Honeywell North selection error is confusing a P100 filter with a chemical cartridge. They protect against different states of matter and are not interchangeable.

  North P100 Filter (7580P100 / 75FFP100) North Chemical Cartridge (N750xx / 75SCx)
Stops Particles: dust, mist, fume, spores Gases and vapors by sorbent class
Does NOT stop Any gas or vapor Particulate, unless a P100 version is used
Use for Silica, lead, welding fume, mold Solvents, acid gas, ammonia, multi-gas
Both at once Use a P100 combination (7581/7582/7583/7584P100L or 75SCP100L) Use a P100 combination (7581/7582/7583/7584P100L or 75SCP100L)

For the full explanation, see Organic Vapor vs P100.

Honeywell North Cartridge Job / Industry Selection

Job / Industry Recommended North Cartridge Guide
Spray painting 7581P100L; 7583P100L for 2K paint fumes guide
Solvent cleaning N75001L; 7581P100L if mist solvents guide
Mold remediation 7580P100 / 75FFP100; 75SCP100L for odor mold guide
Silica dust 7580P100 or 75FFP100 silica guide
Fiberglass 7581P100L (resin vapor + dust) Organic Vapor vs P100
Welding fumes 7580P100; 7583P100L for coated metal welding guide
Pesticides 7583P100L or 7584P100L pesticides guide
Ammonia handling N75004L; 7584P100L with particulate ammonia guide
Chlorine / acid gas N75002L; 7582P100L with mist chlorine guide
Formaldehyde 7582P100L or 75SCP100L formaldehyde guide
Facility maintenance 75SCP100L (multi + P100) North filters overview
Emergency preparedness 75SCP100L or 7584P100L cartridge selection guide

Best Honeywell North Cartridge by Hazard

What Honeywell North Cartridge Is Best for Paint Fumes?

Answer: Paint fumes are organic vapor plus overspray, so the 7581P100L (organic vapor + P100) is the best Honeywell North cartridge for paint fumes — it stops both the solvent vapor and the mist. Use the N75001L for brush and roll with no mist, and the 7583P100L for two-component coatings. P100 included: yes. Product: Honeywell North 7581P100L Organic Vapor / P100 Cartridge; review: 7581P100L Review. See the North cartridge for paint fumes guide.

What Honeywell North Cartridge Is Best for Organic Vapor?

Answer: For organic vapor with no particulate, the N75001L organic vapor cartridge is the focused choice. When mist or dust is also present, step up to the 7581P100L, which adds a P100. Confirm the solvent is within the organic-vapor NIOSH approval. P100 included: no. Product: Honeywell North N75001L Organic Vapor Cartridge; review: N75001L Review. See the North cartridge for solvents guide.

What Honeywell North Cartridge Is Best for Acid Gas?

Answer: For acid gases such as chlorine, hydrogen chloride, and sulfur dioxide, use the N75002L (vapor only) or the 7582P100L (acid gas, formaldehyde, and P100) when particulate is present. Cartridges are valid only below each gas IDLH; above it, use supplied air. P100 included: yes. Product: Honeywell North 7582P100L Acid Gas / Formaldehyde / P100 Cartridge; review: 7582P100L Review. See the acid gas cartridge guide.

What Honeywell North Cartridge Is Best for Ammonia?

Answer: Ammonia needs a dedicated ammonia/methylamine sorbent — the N75004L, or the 7584P100L when particulate is present. The 75SCP100L also covers ammonia. Acid-gas and organic-vapor cartridges do not protect against ammonia. P100 included: no. Product: Honeywell North N75004L Ammonia/Methylamine Cartridge; review: N75004L Review. See the North cartridge for ammonia guide.

What Honeywell North Cartridge Is Best for Formaldehyde?

Answer: The 7582P100L (acid gas, formaldehyde, and P100) is the focused Honeywell North choice for formaldehyde, and the broad 75SCP100L multi-contaminant cartridge also covers it. Both include P100. An organic-vapor-only cartridge is not the right choice for formaldehyde. P100 included: yes. Product: Honeywell North 7582P100L Acid Gas / Formaldehyde / P100 Cartridge; review: 7582P100L Review. See the formaldehyde cartridge guide.

What Honeywell North Cartridge Is Best for Silica Dust?

Answer: Silica is particulate, so the best Honeywell North choice is a P100 filter — the 7580P100 or 75FFP100 at 99.97% efficiency. No gas or vapor cartridge is needed unless chemicals are also present. P100 included: Yes (standalone). Product: Honeywell North 7580P100 P100 Filter; review: 7580P100 Review. See the North cartridge for silica guide.

What Honeywell North Cartridge Is Best for Welding Fumes?

Answer: Welding fume is particulate, so a North P100 (7580P100 / 75FFP100) is the baseline. For galvanized, painted, or coated metal that off-gasses vapors and acid gases, use the 7583P100L (organic vapor + acid gas + P100). Production welding often uses a PAPR. P100 included: Yes (standalone). Product: Honeywell North 7580P100 P100 Filter; review: 7580P100 Review. See the North cartridge for welding guide.

What Honeywell North Cartridge Is Best for Mold Remediation?

Answer: Mold spores are particulate, so a North P100 (7580P100 / 75FFP100) is the core protection. For the musty odor and biocides, the 75SCP100L adds vapor relief. N95 is the EPA minimum for small jobs; P100 is the professional standard. P100 included: Yes (standalone). Product: Honeywell North 7580P100 P100 Filter; review: 7580P100 Review. See the North cartridge for mold guide.

What Honeywell North Cartridge Is Best for Solvents?

Answer: Solvents are organic vapor, so the N75001L is the core Honeywell North cartridge, or the 7581P100L when spraying or mist is present. A few solvents fall outside organic-vapor approval and require supplied air — always check the SDS. P100 included: no. Product: Honeywell North N75001L Organic Vapor Cartridge; review: N75001L Review. See the North cartridge for solvents guide.

Honeywell North Cartridge Model Profiles

Honeywell North 7580P100 Cartridge Overview

Honeywell North 7580P100 P100 Filter. Particulates only — silica, lead, asbestos, welding fume, and mold spores at 99.97%.

  • Best for: Construction silica, lead, welding fume, demolition dust
  • Protects against: Particulates only — silica, lead, asbestos, welding fume, and mold spores at 99.97%
  • Does not protect against: Any gas or vapor (organic vapor, acid gas, ammonia)
  • P100 included: Yes (standalone)
  • Compatible respirators: North 5500, 7700, 5400, 7600
  • Links: Honeywell North 7580P100 P100 Filter • 7580P100 Review

Do Not Use 7580P100 For

  • organic vapors or paint fumes
  • solvents or fuel vapor
  • acid gas such as chlorine or SOâ‚‚
  • ammonia or methylamine
  • any gas — it is a particulate filter only
Specification Detail
Manufacturer Honeywell North
Model 7580P100
Protection type P100 particulate filter
P100 included Yes (standalone)
Cartridge/filter type Particulate filter
Best applications Construction silica, lead, welding fume, demolition dust
Compatible respirator family North 5500, 7700, 5400, 7600

Honeywell North 75FFP100 Cartridge Overview

Honeywell North 75FFP100 P100 Filter. Particulates only — dust, mist, fume, and spores at 99.97%, in a low-profile disc.

  • Best for: Silica, lead, asbestos, welding fume, mold spores
  • Protects against: Particulates only — dust, mist, fume, and spores at 99.97%, in a low-profile disc
  • Does not protect against: Any gas or vapor
  • P100 included: Yes (standalone)
  • Compatible respirators: North 5500, 7700, 5400, 7600
  • Links: Honeywell North 75FFP100 P100 Filter • 75FFP100 Review

Do Not Use 75FFP100 For

  • organic vapors or solvents
  • acid gas or chlorine
  • ammonia
  • paint fumes
  • any gas — particulate only
Specification Detail
Manufacturer Honeywell North
Model 75FFP100
Protection type P100 particulate filter
P100 included Yes (standalone)
Cartridge/filter type Particulate filter
Best applications Silica, lead, asbestos, welding fume, mold spores
Compatible respirator family North 5500, 7700, 5400, 7600

Honeywell North N75001L Cartridge Overview

Honeywell North N75001L Organic Vapor Cartridge. Organic vapors — solvents, fuels, paint vapor, adhesives.

  • Best for: Brush/roll painting, degreasing, solvent wipe-down with no mist
  • Protects against: Organic vapors — solvents, fuels, paint vapor, adhesives
  • Does not protect against: Particulate (no P100), acid gas, ammonia
  • P100 included: No
  • Compatible respirators: North 5500, 7700, 5400, 7600
  • Links: Honeywell North N75001L Organic Vapor Cartridge • N75001L Review

Do Not Use N75001L For

  • dust, mist, or spray particulate by itself (pair with a filter/prefilter)
  • acid gas such as chlorine or HCl
  • ammonia or methylamine
  • silica, lead, or welding fume
Specification Detail
Manufacturer Honeywell North
Model N75001L
Protection type Organic vapor cartridge
P100 included No
Cartridge/filter type Gas/vapor cartridge
Best applications Brush/roll painting, degreasing, solvent wipe-down with no mist
Compatible respirator family North 5500, 7700, 5400, 7600

Honeywell North 7581P100L Cartridge Overview

Honeywell North 7581P100L Organic Vapor / P100 Cartridge. Organic vapors plus particulate — solvents and overspray mist together.

  • Best for: Spray painting, solvent work with dust or mist, fiberglass resin
  • Protects against: Organic vapors plus particulate — solvents and overspray mist together
  • Does not protect against: Acid gas, ammonia, formaldehyde (unless approved)
  • P100 included: Yes
  • Compatible respirators: North 5500, 7700, 5400, 7600
  • Links: Honeywell North 7581P100L Organic Vapor / P100 Cartridge • 7581P100L Review

Do Not Use 7581P100L For

  • ammonia or methylamine
  • formaldehyde unless specifically approved
  • acid-gas-only hazards (use the 7582P100L)
  • exposures above the contaminant IDLH
Specification Detail
Manufacturer Honeywell North
Model 7581P100L
Protection type Organic vapor + P100 combination
P100 included Yes
Cartridge/filter type Gas/vapor cartridge
Best applications Spray painting, solvent work with dust or mist, fiberglass resin
Compatible respirator family North 5500, 7700, 5400, 7600

Honeywell North N75002L Cartridge Overview

Honeywell North N75002L Acid Gas Cartridge. Acid gases — chlorine, hydrogen chloride, sulfur dioxide, hydrogen fluoride.

  • Best for: Chlorine and acid-gas vapor work with no particulate
  • Protects against: Acid gases — chlorine, hydrogen chloride, sulfur dioxide, hydrogen fluoride
  • Does not protect against: Particulate (no P100), organic vapor, ammonia
  • P100 included: No
  • Compatible respirators: North 5500, 7700, 5400, 7600
  • Links: Honeywell North N75002L Acid Gas Cartridge • N75002L Review

Do Not Use N75002L For

  • organic vapor or solvents
  • ammonia
  • dust, mist, or particulate
  • exposures above the gas IDLH (use supplied air)
Specification Detail
Manufacturer Honeywell North
Model N75002L
Protection type Acid gas cartridge
P100 included No
Cartridge/filter type Gas/vapor cartridge
Best applications Chlorine and acid-gas vapor work with no particulate
Compatible respirator family North 5500, 7700, 5400, 7600

Honeywell North 7582P100L Cartridge Overview

Honeywell North 7582P100L Acid Gas / Formaldehyde / P100 Cartridge. Acid gases (chlorine, HCl, SOâ‚‚), formaldehyde, plus P100 particulate.

Do Not Use 7582P100L For

  • organic vapor or solvents (no organic-vapor sorbent)
  • ammonia
  • exposures above the gas IDLH
Specification Detail
Manufacturer Honeywell North
Model 7582P100L
Protection type Acid gas + formaldehyde + P100 combination
P100 included Yes
Cartridge/filter type Gas/vapor cartridge
Best applications Acid-gas and formaldehyde work with mist or dust — water treatment, labs
Compatible respirator family North 5500, 7700, 5400, 7600

Honeywell North 7583P100L Cartridge Overview

Honeywell North 7583P100L Organic Vapor / Acid Gas / P100 Cartridge. Organic vapor, acid gas, and P100 particulate.

Do Not Use 7583P100L For

  • ammonia or methylamine
  • pure particulate jobs where a P100 disc is cheaper
  • exposures above the gas IDLH
Specification Detail
Manufacturer Honeywell North
Model 7583P100L
Protection type Organic vapor + acid gas + P100 combination
P100 included Yes
Cartridge/filter type Gas/vapor cartridge
Best applications Two-component/isocyanate paint, coated-metal welding, mixed chemical + dust
Compatible respirator family North 5500, 7700, 5400, 7600

Honeywell North 7584P100L Cartridge Overview

Honeywell North 7584P100L Ammonia/Methylamine/P100 Cartridge. Ammonia, methylamine, plus P100 particulate.

  • Best for: Ammonia work with dust or mist — refrigeration, wastewater, fertilizer
  • Protects against: Ammonia, methylamine, plus P100 particulate
  • Does not protect against: Acid-gas-only or organic-vapor-only as primary hazard
  • P100 included: Yes
  • Compatible respirators: North 5500, 7700, 5400, 7600
  • Links: Honeywell North 7584P100L Ammonia/Methylamine/P100 Cartridge • 7584P100L Review

Do Not Use 7584P100L For

  • acid-gas-only or organic-vapor-only hazards as the primary need
  • ammonia above the 300 ppm IDLH
  • as a substitute for hazard assessment
Specification Detail
Manufacturer Honeywell North
Model 7584P100L
Protection type Ammonia / methylamine + P100 combination
P100 included Yes
Cartridge/filter type Gas/vapor cartridge
Best applications Ammonia work with dust or mist — refrigeration, wastewater, fertilizer
Compatible respirator family North 5500, 7700, 5400, 7600

Honeywell North 75SCP100L Cartridge Overview

Honeywell North 75SCP100L Multi-Contaminant/P100 Cartridge. Organic vapor, acid gas, ammonia, methylamine, formaldehyde, plus P100.

  • Best for: Water treatment, facility maintenance, mixed or uncharacterized exposures
  • Protects against: Organic vapor, acid gas, ammonia, methylamine, formaldehyde, plus P100
  • Does not protect against: Confined-space or above-IDLH atmospheres
  • P100 included: Yes
  • Compatible respirators: North 5500, 7700, 5400, 7600
  • Links: Honeywell North 75SCP100L Multi-Contaminant/P100 Cartridge • 75SCP100L Review

Do Not Use 75SCP100L For

  • confined-space or above-IDLH atmospheres (use supplied air)
  • as a reason to skip a documented hazard assessment
Specification Detail
Manufacturer Honeywell North
Model 75SCP100L
Protection type Multi-contaminant (OV/AG/ammonia/methylamine/formaldehyde) + P100
P100 included Yes
Cartridge/filter type Gas/vapor cartridge
Best applications Water treatment, facility maintenance, mixed or uncharacterized exposures
Compatible respirator family North 5500, 7700, 5400, 7600

Honeywell North 75SCL Cartridge Overview

Honeywell North 75SCL Defender Multi-Gas Cartridge. Broad gas/vapor — organic vapor, acid gas, ammonia, methylamine, formaldehyde.

  • Best for: Broad multi-gas vapor where no particulate is present, low profile
  • Protects against: Broad gas/vapor — organic vapor, acid gas, ammonia, methylamine, formaldehyde
  • Does not protect against: Particulate (no P100), confined-space/above-IDLH
  • P100 included: No
  • Compatible respirators: North 5500, 7700, 5400, 7600
  • Links: Honeywell North 75SCL Defender Multi-Gas Cartridge • 75SCL Review

Do Not Use 75SCL For

  • any job where P100 particulate protection is required (it has NO P100)
  • silica, lead, welding fume, or spray mist
  • confined-space or above-IDLH atmospheres
Specification Detail
Manufacturer Honeywell North
Model 75SCL
Protection type Defender multi-purpose multi-gas cartridge (NO integrated P100)
P100 included No
Cartridge/filter type Gas/vapor cartridge
Best applications Broad multi-gas vapor where no particulate is present, low profile
Compatible respirator family North 5500, 7700, 5400, 7600

Honeywell North Cartridge Cross Reference Chart

Closest 3M equivalents by protection class. These are reference equivalents only — Honeywell North cartridges do not fit 3M respirators and are not interchangeable. Match the cartridge brand to your facepiece.

Honeywell North Model Protection Type P100 Included? Closest 3M Equivalent Best Use WC Safety Review
7580P100 P100 particulate filter Yes (standalone) 3M 2091 (P100) Silica, lead, mold, welding fume (particulate) 7580P100 Review
75FFP100 P100 particulate filter Yes (standalone) 3M 2091 / 2096 (P100) Dust, fume, spores (low-profile P100) 75FFP100 Review
N75001L Organic vapor cartridge No 3M 6001 (organic vapor) Paint fumes, solvents, organic vapor N75001L Review
7581P100L Organic vapor + P100 combination Yes 3M 60921 (OV/P100) Spray painting, solvent + dust 7581P100L Review
7582P100L Acid gas + formaldehyde + P100 combination Yes 3M 60922 (acid gas/P100) Acid gas + formaldehyde + mist 7582P100L Review
7583P100L Organic vapor + acid gas + P100 combination Yes 3M 60923 (OV/acid gas/P100) 2K paint, coated-metal welding 7583P100L Review
7584P100L Ammonia / methylamine + P100 combination Yes 3M 60924 (ammonia/P100) Ammonia + dust/mist 7584P100L Review
75SCL Defender multi-purpose multi-gas cartridge (NO integrated P100) No 3M 6006 (multi-gas) Multi-gas vapor (no particulate) 75SCL Review
75SCP100L Multi-contaminant (OV/AG/ammonia/methylamine/formaldehyde) + P100 Yes 3M 60926 (multi-gas/P100) Multi-gas + particulate (maintenance) 75SCP100L Review

For the full 3M lineup, see the 3M Filter & Cartridge Guide.

When Should You Replace Honeywell North Cartridges?

Cartridge Type Replace When Signs of Saturation Notes
P100 filter (7580P100 / 75FFP100) Breathing resistance rises, or soiled/wet/damaged Harder to inhale; visible loading No chemical saturation — mechanical loading only
Organic vapor (N75001L / 7581P100L) Per written change schedule; at odor/taste breakthrough Solvent smell or taste through the mask Warning properties unreliable — use a data-based schedule
Acid gas (N75002L / 7582P100L) Per change schedule; at odor/irritation Sharp odor or eye/throat irritation Valid only below the gas IDLH
Ammonia (N75004L / 7584P100L) Per change schedule; at any ammonia odor Pungent ammonia smell through the mask Strong odor warns of breakthrough — act on it
Multi-gas (75SCL / 75SCP100L) Per change schedule; at any odor breakthrough Any contaminant odor or taste Verify each gas on the NIOSH approval
Combination P100 cartridges Vapor side per schedule; P100 side on resistance Odor breakthrough or rising resistance Two replacement triggers — gas saturation and particulate loading

Odor or taste breakthrough means leave the area immediately and replace the cartridge. P100 filters are replaced when breathing resistance increases or the filter is damaged, dirty, or contaminated. Gas and vapor cartridges need a written change-out schedule for occupational use. See how long do respirator cartridges last and OSHA 29 CFR 1910.134.

Honeywell North Cartridge Reviews and Comparisons

Honeywell North 7580P100 vs 75FFP100

Both are Honeywell North P100 particulate filters at 99.97% and are equal for particulate-only exposure such as silica, lead, and welding fume; neither protects against any gas or vapor. For P100 protection they are interchangeable — the 75FFP100 is lower-profile, the 7580P100 a sturdier bayonet disc. Honeywell North 7580P100 vs 75FFP100.

Honeywell North N75001L vs 7581P100L

Both use the same Honeywell North organic vapor sorbent, so for gases and vapors they are equal. The 7581P100L adds a P100 particulate filter, so it is better for any particulate or overspray and is required when P100 protection is needed; the N75001L is better for pure organic vapor with no mist. Honeywell North N75001L vs 7581P100L.

Honeywell North 7583P100L vs 75SCP100L

Both include a P100 particulate filter, so for particulate they are equal. The 7583P100L is a focused organic vapor and acid gas cartridge — better for defined organic-vapor-and-acid-gas tasks. The 75SCP100L is broader multi-contaminant (adds ammonia and formaldehyde) — better for mixed or uncharacterized atmospheres. Full comparison: Honeywell North 7583P100L vs 75SCP100L.

Honeywell North 75SCL vs 75SCP100L

Both are broad Honeywell North multi-gas cartridges with the same gas and vapor coverage. The difference is particulate: the 75SCP100L includes a P100 particulate filter, the 75SCL Defender does not. For particulate-only or combined exposure the 75SCP100L is better; choose the 75SCL only when no particulate is present. Full comparison: Honeywell North 75SCL vs 75SCP100L.

Honeywell North 75SCL vs 3M 6006

Both are multi-gas vapor cartridges without an integrated P100 particulate filter, so for gases and vapors they are closely matched and neither protects against particulate alone. The choice is brand: the Honeywell North 75SCL fits North facepieces, the 3M 6006 fits 3M. Full comparison: Honeywell North 75SCL vs 3M 6006.

Honeywell North 75SCL vs 3M 60926

The 3M 60926 includes a P100 particulate filter while the Honeywell North 75SCL does not, so the 60926 is better whenever particulate is present and when P100 is required; for gas and vapor coverage they are broadly comparable. The Honeywell North 75SCP100L is the closer like-for-like to the 3M 60926. Full comparison: Honeywell North 75SCL vs 3M 60926.

Honeywell North 7583P100L vs 3M 60923

Both are organic vapor, acid gas, and P100 particulate combination cartridges and are functionally comparable for mixed organic-vapor-and-acid-gas work with particulate. They are not interchangeable: the Honeywell North 7583P100L fits North facepieces, the 3M 60923 fits 3M. Full comparison: Honeywell North 7583P100L vs 3M 60923.

Honeywell North 7581P100L vs 3M 60921

Both are organic vapor plus P100 particulate combination cartridges and are the closest cross-brand equivalents — comparable for organic vapor and for particulate or overspray. They are not interchangeable: the Honeywell North 7581P100L fits North facepieces, the 3M 60921 fits 3M. Full comparison: Honeywell North 7581P100L vs 3M 60921.

Common Honeywell North Cartridge Selection Mistakes

  • Using P100 for organic vapors. A P100 filter stops particles only — never solvent vapor, acid gas, or ammonia.
  • Using organic vapor cartridges for acid gas. The N75001L will not capture chlorine or SOâ‚‚; use the N75002L or 7582P100L.
  • Using the N75001L without particulate filtration when dust is present. Add P100 — the 7581P100L — when overspray or dust is in the air.
  • Assuming the 75SCL includes P100. The 75SCL Defender is a multi-gas cartridge with no integrated P100; use the 75SCP100L when particulate is present.
  • Assuming Honeywell North cartridges fit 3M respirators. North cartridges fit only North facepieces.
  • Ignoring cartridge change-out schedules. Waiting to smell breakthrough means exposure already happened — use a written schedule under OSHA 1910.134.
  • Choosing by color instead of contaminant. Confirm the cartridge contaminant class and NIOSH approval, not just the label color.

Honeywell North Cartridge FAQ

What Honeywell North cartridge do I need?

Match the cartridge to your contaminant: particulate uses the 7580P100 or 75FFP100; organic vapor uses the N75001L or 7581P100L; acid gas uses the N75002L or 7582P100L; ammonia uses the N75004L or 7584P100L; mixed or uncharacterized atmospheres use the 75SCP100L. The quick selection chart above maps each exposure to the right SKU.

Are Honeywell North cartridges universal?

They share one universal North bayonet across the 7700, 5500, 7600, and 5400 facepieces, so any North cartridge fits any North respirator. But that mount is proprietary — North cartridges do not fit 3M, MSA, or Moldex. Universal applies only within the Honeywell North lineup.

Which Honeywell North cartridge is best for paint fumes?

The 7581P100L (organic vapor + P100) is the Honeywell North cartridge for paint fumes, because spraying produces solvent vapor plus overspray mist. Use the N75001L for brush and roll with no mist, and the 7583P100L for two-component or isocyanate coatings.

Which Honeywell North cartridge is best for organic vapor?

The N75001L organic vapor cartridge is the core choice for solvents and organic vapor with no particulate. Add P100 with the 7581P100L when mist or dust is present. Confirm the specific solvent is within the organic-vapor NIOSH approval.

Which Honeywell North cartridge is best for ammonia?

Ammonia needs a dedicated ammonia/methylamine sorbent — the N75004L, or the 7584P100L when particulate is present. The 75SCP100L multi-contaminant cartridge also covers ammonia. Acid-gas and organic-vapor cartridges do not protect against ammonia.

Which Honeywell North cartridge is best for acid gas?

For acid gases such as chlorine, hydrogen chloride, and sulfur dioxide, use the N75002L, or the 7582P100L (acid gas + formaldehyde + P100) when particulate is present. The 75SCP100L also covers acid gas. Cartridges are valid only below each gas IDLH.

Which Honeywell North cartridge is best for formaldehyde?

The 7582P100L (acid gas + formaldehyde + P100) is the focused Honeywell North choice for formaldehyde, and the 75SCP100L multi-contaminant cartridge also covers formaldehyde in a broader mix. Both include P100. The N75001L organic vapor cartridge alone is not the right choice for formaldehyde.

Which Honeywell North cartridge is best for silica dust?

Silica is particulate, so the best Honeywell North choice is a P100 filter — the 7580P100 or 75FFP100 at 99.97%. No gas or vapor cartridge is needed unless chemicals are also present.

Does P100 protect against organic vapors?

No. A Honeywell North P100 filter stops particles only — dust, mist, fume, and spores. It provides zero protection against organic vapors, acid gas, or ammonia. For vapors you need a chemical cartridge; for both, use a combination such as the 7581P100L.

What is the difference between the 7580P100 and 75FFP100?

Both are North P100 particulate filters at 99.97% and are functionally equivalent. The 75FFP100 is a low-profile disc; the 7580P100 is the bayonet P100 cartridge. Choose whichever your facepiece kit specifies — neither provides gas or vapor protection.

What is the difference between the 75SCL and 75SCP100L?

Both are broad North multi-gas cartridges covering organic vapor, acid gas, ammonia, methylamine, and formaldehyde. The key difference is particulate: the 75SCP100L includes a P100 filter, while the 75SCL Defender has no integrated P100. Choose the 75SCP100L when dust, mist, or fume is present.

What is the difference between the N75001L and 7581P100L?

The N75001L is a Honeywell North organic vapor cartridge with no particulate filter. The 7581P100L adds an integrated P100, covering organic vapor and particulate together. Choose the N75001L for pure vapor and the 7581P100L when overspray or dust is present.

Can Honeywell North cartridges fit 3M respirators?

No. Honeywell North cartridges fit only North facepieces via the North bayonet and will not seal on a 3M, MSA, or Moldex respirator. Match the cartridge brand to your respirator brand; cross-brand mixing creates a seal-failure risk and is never NIOSH-approved.

When should Honeywell North cartridges be replaced?

Replace gas and vapor cartridges on a written change schedule under OSHA 1910.134(d)(3), and immediately at any odor, taste, or irritation through the mask. Replace P100 filters when breathing resistance rises or they are soiled, wet, or damaged. Never rely on smell as your only indicator.

Which Honeywell North cartridge is closest to the 3M 60926?

The Honeywell North 75SCP100L multi-contaminant + P100 cartridge is the closest equivalent to the 3M 60926 multi-gas + P100 cartridge — both cover a broad mix of gases plus 99.97% particulate. They are not interchangeable across facepieces; use the 75SCP100L on North respirators and the 3M 60926 on 3M respirators.

Disclosures & editorial standards. WC Safety participates in the Amazon Services LLC Associates Program; outbound Amazon links are affiliate links. We accept no manufacturer payment. This content is product-selection education, not medical, legal, or regulatory advice; respirator selection must follow a documented hazard assessment and fit testing under OSHA 29 CFR 1910.134.
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