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Honeywell North 75SCP100L Multi-Contaminant P100 Respirator Cartridge

Honeywell North SKU: 75SCP100L Respirator Cartridges
β˜† β˜† β˜† β˜† β˜† 4.86 (1336 reviews on WC Safety)
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EDITORIAL REVIEW: 4.8/5 Independently reviewed by WC Safety "Editorial Pick β€” broadest North-line coverage at the lowest combination cartridge price" Read the full review β†’ Β· 2026 Nort...

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Multi Gas P100

Honeywell North 75SCP100L β€” OV + Acid Gas + Ammonia + P100, NIOSH 42 CFR 84, WC Safety Editorial Pick

The Honeywell North 75SCP100L is a NIOSH 42 CFR 84 multi-contaminant P100 combination cartridge providing the broadest single-cartridge protection in the Honeywell North line: organic vapor, acid gas (HCl, HF, SOβ‚‚, Clβ‚‚, Hβ‚‚S), ammonia/methylamine, and 99.97% P100 particulate filtration β€” sold as a pair on the North bayonet system. It is WC Safety's Editorial Pick for the best-value cartridge in the North line, covering four hazard classes at a price at or below single-class alternatives. The 75SCP100L is the correct default when the hazard profile is not fully characterized by air monitoring, or when multiple gas classes are confirmed. For environments where particles are absent, the 75SCL gas-only Defender provides the same gas coverage at lower breathing resistance. Compatible with all North 7700, 5500, 5400, and 7600 series facepieces.

Quick Facts β€” 75SCP100L
  • Model: Honeywell North 75SCP100L
  • Type: Multi-Contaminant P100 Combination Cartridge β€” sold as a pair
  • NIOSH Approval: 42 CFR 84 OV + Acid Gas + Ammonia/MA + P100
  • Gas Coverage: Organic vapor, HCl, HF, SOβ‚‚, Clβ‚‚, Hβ‚‚S, NH₃, methylamine
  • Particle Coverage: P100 β€” 99.97% all particle types
  • APF (Half-Mask): 10 on North 770030 and 550030 series
  • APF (Full-Face): 50 on North 54001 and 760008 series
  • Connector: North bayonet twist-lock
  • WC Safety recommendation: Default choice for any multi-class or uncertain chemical hazard profile

Key Features

  • WC Safety Editorial Pick: Broadest NIOSH-approved combination cartridge in the Honeywell North line β€” OV + acid gas + ammonia/MA + P100 in a single cartridge, typically priced at or below individual combination alternatives
  • Four-class simultaneous protection: Organic vapor, acid gas (5 species), ammonia/methylamine, and P100 β€” eliminates the need to select between 7581P100L, 7582P100L, 7583P100L, and 7584P100L in environments where multiple classes may be present
  • Correct default for uncertain environments: In facilities where the full chemical hazard profile has not been defined by comprehensive air monitoring, the 75SCP100L provides the broadest coverage available in the North line β€” reducing the risk of selecting an under-specified cartridge
  • Sold as a pair: Two cartridges per package for both positions on a North facepiece
  • Gas-only companion: The 75SCL Defender provides OV + AG + NH₃ without P100 β€” use when the same broad gas coverage is needed but particles are formally confirmed absent

Applications β€” When to Use the 75SCP100L

The 75SCP100L is the default choice for multi-hazard industrial environments and for any situation where the full hazard profile is not fully characterized:

  • Chemical plant and refinery maintenance: Turnaround work involving multiple chemical streams β€” OV (hydrocarbons), Hβ‚‚S, SOβ‚‚, and ammonia may all be co-present in the same operation
  • Wastewater treatment plants: Hβ‚‚S, NH₃, and biological aerosol co-exposure β€” all covered by the 75SCP100L without needing to separate hazard classes
  • Hazmat and emergency response: When the chemical composition of a release is unknown or mixed, the broadest available air-purifying protection is appropriate before supplied-air is donned
  • Multi-process manufacturing: Facilities where workers rotate between solvent operations, acid processes, and ammonia-generating operations during the same shift
  • Agriculture and confined space entry: Grain bins, manure pits, and mixed agricultural operations with OV, NH₃, and dust co-exposure
  • Anywhere the hazard IH data is incomplete: When air monitoring has not been performed for all potential chemical classes, the 75SCP100L provides the broadest defensible coverage available in an air-purifying cartridge

Compatible Respirators

All Honeywell North 7-series and N-series cartridges use the North bayonet twist-lock connector, compatible with the following facepieces.

Respirator Type APF Notes
North 770030S Half-Mask 10 Small
North 770030M Half-Mask 10 Medium β€” start here if unsure of size
North 770030L Half-Mask 10 Large
North 550030S Half-Mask 10 Small β€” silicone facepiece
North 550030M Half-Mask 10 Medium β€” silicone facepiece
North 550030L Half-Mask 10 Large β€” silicone facepiece
North 54001S Full-Face 50 Small β€” integrated eye protection
North 54001 Full-Face 50 M/L β€” integrated eye protection
North 760008AS Full-Face 50 Small β€” wide-view lens
North 760008A Full-Face 50 M/L β€” wide-view lens

North Cartridge & Filter Line β€” Full Comparison

All cartridges use the same North bayonet connector. Select based on documented hazard class.

Model Protection Class Best For
P100 PARTICULATE FILTERS
7580P100 P100 β€” 99.97% Silica, lead, asbestos, welding fume β€” particulate only (2-pack)
75FFP100 P100 β€” 99.97% Same as 7580P100 β€” single unit
COMBINATION CARTRIDGES (GAS + P100)
7581P100L OV + P100 Spray painting, solvents β€” OV and particles confirmed, no acid gas
7582P100L AG + P100 HCl, HF, SOβ‚‚, Clβ‚‚, Hβ‚‚S β€” acid-only, OV formally excluded
7583P100L OV + AG + P100 Mixed chemical environments β€” broader and cheaper than 7582P100L
7584P100L NH₃/MA + P100 Wastewater, agriculture, refrigeration β€” ammonia primary hazard
75SCP100L OV + AG + NH₃ + P100 Multi-hazard / uncertain profile β€” broadest North-line coverage
75852P100L Mercury + Cl + P100 Chlor-alkali, fluorescent lamp recycling β€” only North Hg cartridge
GAS-ONLY CARTRIDGES (NO P100)
N75001L OV only Pure vapor β€” no particles present
N75002L OV + AG Chemical work β€” no particles
N75003L OV + AG + NH₃ Triple gas β€” wastewater, agriculture
N75004L OV + NH₃ OV + ammonia β€” acid gas excluded
75SCL OV + AG + NH₃ Defender series β€” pure gas, lowest breathing resistance
SNAP-ON PREFILTERS
7506N95 N95 snap-on Particle upgrade for gas cartridges β€” dry environments
7506R95 R95 snap-on Oil mist / metalworking upgrade for gas cartridges
7506N99 N99 snap-on Fine silica / pharma upgrade for gas cartridges
7504R95 R95 holder system Oil mist β€” North cartridge holder format

Browse the complete lineup at Honeywell North Respirator Cartridges & Filters β†’

OSHA Compliance

  • NIOSH approval required: All cartridges in OSHA-mandated programs must be NIOSH approved under 42 CFR Part 84
  • Hazard assessment required: OSHA 1910.134(d)(1) β€” cartridge type must match the documented workplace hazard class
  • Fit testing required: OSHA 1910.134(f)(2) β€” annual fit testing for any tight-fitting facepiece, regardless of cartridge type
  • Cartridge change schedule: OSHA 1910.134(d)(3)(iii) β€” end-of-service-life for gas/vapor cartridges must be established before use
  • Medical evaluation: OSHA 1910.134(e) β€” required before fit testing and before operational respirator use

Frequently Asked Questions

What does the 75SCP100L protect against?

Organic vapors, acid gases (HCl, HF, SOβ‚‚, Clβ‚‚, Hβ‚‚S), ammonia and methylamine, and P100 99.97% particle filtration β€” all simultaneously. The broadest NIOSH-approved combination in the North cartridge line. Does not cover mercury vapor (see 75852P100L) or carbon monoxide.

Why is the 75SCP100L the Editorial Pick?

It covers the most hazard classes of any North combination cartridge β€” OV + AG + NH₃ + P100 β€” and is typically priced at or below single-class alternatives like the 7582P100L or 7584P100L. For any environment where the chemical profile includes more than one gas class, the 75SCP100L eliminates the risk of under-specifying. The only reasons to choose a narrower cartridge are confirmed absence of other classes (documented by air monitoring) or the need for lower breathing resistance when particles are absent.

Which respirators does the 75SCP100L fit?

All North bayonet facepieces: North 770030 series (S/M/L), North 550030 series (S/M/L), North 54001 and 54001S, North 760008A and 760008AS.

When should I use the 75SCL instead of the 75SCP100L?

Use the 75SCL when industrial hygiene assessment formally documents that no airborne particles are present in the work environment. The 75SCL provides the same OV + AG + NH₃ gas coverage as the 75SCP100L but without the P100 layer β€” resulting in lower breathing resistance for pure-gas operations.

How do I set a change-out schedule for the 75SCP100L?

OSHA 1910.134(d)(3)(iii) requires a written change schedule established before use. For multi-class cartridges, the schedule is driven by the sorbent class with the shortest service life at the documented concentrations. Your industrial hygienist calculates this based on air monitoring data, contaminant concentration, temperature, humidity, and cartridge capacity. Do not rely on odor breakthrough as a warning signal.

Does the 75SCP100L cover welding fume?

Yes β€” the P100 component covers metal fume, and the OV sorbent covers solvent co-exposure from coatings. For stainless steel welding (Cr VI) or galvanized steel (zinc oxide), the P100 covers the particle hazard; confirm whether additional exposure controls are required for specific metal fume hazards under OSHA substance standards.

What is the APF of the 75SCP100L?

APF 10 on a half-mask. APF 50 on a full-face (North 54001, 760008A). APF applies per hazard class covered.

Does the 75SCP100L work for mercury?

No β€” mercury vapor requires a dedicated mercury-sorbent cartridge. The 75852P100L is the only North cartridge with NIOSH mercury vapor approval.

Is fit testing required?

Yes β€” OSHA 1910.134(f)(2). Annual fit testing for the facepiece before operational use.

Where can I find all North cartridges?

Browse the complete lineup at Honeywell North Respirator Cartridges & Filters β†’

Brand / Vendor
Honeywell North
Model / SKU
75SCP100L
Product Type
Respirator Cartridges
Condition
New
MPN
75SCP100L
Price
$24.49 (Amazon)
Rating
4.86 / 5 β€” 1336 reviews
Availability
βœ“ In Stock on Amazon
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Honeywell North 75SCP100L Multi-Contaminant P100 Respirator Cartridge